ArticleBMJ open2021
Deprescribing intervention activities mapped to guiding principles for use in general practice: a scoping review.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Discontinuing antidepressant medication: a qualitative evidence synthesis and logic model based on health professionals' views.BMC health services research · 2025Pooled it
- Trial
- Trial
- Strengthening Pharmacovigilance Reporting for Withdrawal Reactions to Support Deprescribing.Clinical pharmacology and therapeutics · 2026Review
- Supporting General Practitioners to Deprescribe Benzodiazepines and Z-Drugs in Primary Care: Findings From a Modified Delphi Study.Basic & clinical pharmacology & toxicology · 2026Article
- Mapping care trajectories for hospital-initiated benzodiazepine deprescribing in older adults: a multicentre qualitative study.BMC health services research · 2025Article
- Exploration of Perceptions of Deprescribing Practices Among Doctors in a Low- and Middle-Income Country: A Mixed-Methods Study.Basic & clinical pharmacology & toxicology · 2025Article
- Article
- Factors influencing central nervous system medication deprescribing and behavior change in hospitalized older adults.Journal of the American Geriatrics Society · 2024Article
- Factors influencing healthcare providers' behaviours in deprescribing: a cross-sectional study.Journal of pharmaceutical policy and practice · 2024Article
- Consultation-Based Deprescribing Service to Optimize Palliative Care for Terminal Cancer Patients.Journal of clinical medicine · 2023Article
- What makes a multidisciplinary medication review and deprescribing intervention for older people work well in primary care? A realist review and synthesis.BMC geriatrics · 2023Review
- Uptake of pharmacist recommendations by patients after discharge: Implementation study of a patient-centered medicines review service.BMC geriatrics · 2023Article
- Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of thePrimary health care research & development · 2023Article
- Antipsychotic Medication Use Among Older Adults Following Infection-Related Hospitalization.JAMA network open · 2023Article
- Withdrawal of antihypertensive medication in young to middle-aged adults: a prospective, single-group, intervention study.Clinical hypertension · 2023Article
- General Practice Patients' Experiences and Perceptions of the WiserAD Structured Web-Based Support Tool for Antidepressant Deprescribing: Protocol for a Mixed Methods Case Study With Realist Evaluation.JMIR research protocols · 2022Article
- Recent Updates on Risk and Management Plans Associated with Polypharmacy in Older Population.Geriatrics (Basel, Switzerland) · 2022Article
- Prevalence and Severity of Potential Drug-Drug Interactions in Patients with Multiple Sclerosis with and without Polypharmacy.Pharmaceutics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify and characterise activities for deprescribing used in general practice and to map the identified activities to pioneering principles of deprescribing.
settingPrimary care. DATA SOURCES: Medline, EMBASE (Ovid), CINAHL, Australian New Zealand Clinical Trials Registry (ANZCTR), Clinicaltrials.gov, ISRCTN registry, OpenGrey, STUDY SELECTION: Included studies were original research (randomised controlled trial, quasi-experimental, cohort study, qualitative and case studies), protocol papers and protocol registrations. DATA EXTRACTION: Screening and data extraction was completed by one reviewer; 10% of the studies were independently reviewed by a second reviewer. Coding of full-text articles in NVivo was conducted and mapped to five deprescribing principles.
resultsFifty studies were included. The most frequently used activities were identification of appropriate patients for deprescribing (76%), patient education (50%), general practitioners (GP) education (48%), and development and use of a tapering schedule (38%). Six activities did not align with the five deprescribing principles. As such, two principles (engage practice staff in education and appropriate identification of patients, and provide feedback to staff about deprescribing occurrences within the practice) were added.
conclusionActivities and guiding principles for deprescribing should be paired together to provide an accessible and comprehensive guide to deprescribing by GPs. The addition of two principles suggests that practice staff and practice management teams may play an instrumental role in sustaining deprescribing processes within clinical practice. Future research is required to determine the most of effective activities to use within each principle and by whom.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.