Evidence map›Paper›PMID 34488941›Full record

ArticleeLife2021

Ancient role of sulfakinin/cholecystokinin-type signalling in inhibitory regulation of feeding processes revealed in an echinoderm.

Ana B Tinoco, Antón Barreiro-Iglesias, Luis Alfonso Yañez Guerra, Jérôme Delroisse, Ya Zhang, Elizabeth F Gunner, Cleidiane G Zampronio, Alexandra M Jones, Michaela Egertová, Maurice R Elphick

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  5. Discovery and functional characterization of a bombesin-type neuropeptide signaling system in an invertebrate.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Ana B Tinoco *Queen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0003-0525-4475
Antón Barreiro-Iglesias *Queen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0002-7507-080X
Luis Alfonso Yañez Guerra *Queen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0002-2523-1310
Jérôme DelroisseQueen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0002-9233-6470
Ya ZhangQueen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0002-2158-0660
Elizabeth F GunnerQueen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.
Cleidiane G ZampronioSchool of Life Sciences and Proteomics, Research Technology Platform, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-0934-0792
Alexandra M JonesSchool of Life Sciences and Proteomics, Research Technology Platform, University of Warwick, Coventry, United Kingdom.ORCID 0000-0003-2571-8708
Michaela EgertováQueen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.
Maurice R ElphickQueen Mary University of London, School of Biological & Behavioural Sciences, London, United Kingdom.ORCID 0000-0002-9169-0048
Queen Mary University of London · GBUniversity of Warwick · GBUniversity of Mons · BE

Funding

Biotechnology and Biological Sciences Research Council BB/M001032/1Biotechnology and Biological Sciences Research Council BB/M001644/1
6 · The paper itself

Abstract

Sulfakinin (SK)/cholecystokinin (CCK)-type neuropeptides regulate feeding and digestion in protostomes (e.g. insects) and chordates. Here, we characterised SK/CCK-type signalling for the first time in a non-chordate deuterostome - the starfish

Indexed as

AnimalsAsteriasCalcium-Calmodulin-Dependent Protein KinasesCell LineCholecystokininEchinodermataNervous SystemNeuropeptidesPhylogenySignal TransductionStarfishCalcium-Calmodulin-Dependent Protein KinasesCholecystokininNeuropeptidesAsterias rubensevolutionary biologyfeedingneuropeptidesreceptorsstarfishsulfakinin/cholecystokinin

Identifiers

PMID34488941
PMCPMC8428848
OpenAlexW3197223231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.