ArticleRadiation oncology (London, England)2021
A dosimetric and radiobiological evaluation of VMAT following mastectomy for patients with left-sided breast cancer.
Article in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- A clinical trial to compare a 3D-printed bolus with a conventional bolus with the aim of reducing cardiopulmonary exposure in postmastectomy patients with volumetric modulated arc therapy.Cancer medicine · 2022Trial
- Integrating static angle ports and dynamic collimator rotation in volumetric modulated arc therapy for hypofractionated whole breast irradiation in Chinese females: a single-centre dosimetric study.Radiation oncology (London, England) · 2026Article
- Effect of different bolus application methods on target dose in radiotherapy after radical mastectomy.Frontiers in oncology · 2026Article
- Comparative dosimetric and radiobiological assessment of a hybrid-VMAT strategy incorporating supplemental short-arcs for left-sided postmastectomy radiotherapy.Frontiers in oncology · 2026Article
- Risk factors for early-onset radiodermatitis in patients with locally advanced breast cancer: a comparative analysis of volumetric modulated arc therapy and intensity-modulated radiotherapy.Breast cancer (Tokyo, Japan) · 2025Article
- Dosimetric effect of silicone-based gel on skin surface during volumetric modulated arc therapy for breast cancer.Journal of applied clinical medical physics · 2025Article
- Effect of jaw width in jaw tracking mode on the radiotherapy dose of partial arc VMAT in patients undergoing left breast-conserving surgery.Scientific reports · 2025Article
- Why is Volumetric Modulated Arc Therapy Not Considered the Standard of Care for Locoregional Radiation Therapy for Breast Cancer Patients?Advances in radiation oncology · 2025Article
- Effect of physical parameter differences on the performance of a knowledge-based partial arc VMAT RapidPlan model for left breast cancer.Frontiers in oncology · 2025Article
- Post-mastectomy radiotherapy: Impact of bolus thickness and irradiation technique on skin dose.Zeitschrift fur medizinische Physik · 2024Article
- Correlations between patient-specific parameters and dosimetric indices for personalized breast cancer radiotherapy.Scientific reports · 2024Article
- Dosimetric benefit and clinical feasibility of deep inspiration breath-hold and volumetric modulated arc therapy-based postmastectomy radiotherapy for left-sided breast cancer.Scientific reports · 2024Article
- Utilizing radiomics and dosiomics with AI for precision prediction of radiation dermatitis in breast cancer patients.BMC cancer · 2024Article
- Exploring Helium Ions' Potential for Post-Mastectomy Left-Sided Breast Cancer Radiotherapy.Cancers · 2024Article
- Comparative Study of Plan Robustness for Breast Radiotherapy: Volumetric Modulated Arc Therapy Plans with Robust Optimization versus Manual Flash Approach.Diagnostics (Basel, Switzerland) · 2023Article
- Comparing brass mesh to tissue equivalent bolus materials for volumetric modulated arc therapy chest wall irradiation.Journal of applied clinical medical physics · 2023Article
- Current Cardioprotective Strategies for the Prevention of Radiation-Induced Cardiotoxicity in Left-Sided Breast Cancer Patients.Journal of personalized medicine · 2023Review
- A Dosimetric and Radiobiological Comparison of Intensity Modulated Radiotherapy, Volumetric Modulated Arc Therapy and Helical Tomotherapy Planning Techniques in Synchronous Bilateral Breast Cancer.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Risk factors for radiation pneumonitis after rotating gantry intensity-modulated radiation therapy for lung cancer.Scientific reports · 2022Article
- Heart Sparing Radiotherapy Techniques in Breast Cancer: A Focus on Deep Inspiration Breath Hold.Breast cancer (Dove Medical Press) · 2022Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTo compare the dosimetric, normal tissue complication probability (NTCP), secondary cancer complication probabilities (SCCP), and excess absolute risk (EAR) differences of volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) for left-sided breast cancer after mastectomy. METHODS AND MATERIALS: Thirty patients with left-sided breast cancer treated with post-mastectomy radiation therapy (PMRT) were randomly enrolled in this study. Both IMRT and VMAT treatment plans were created for each patient. Planning target volume (PTV) doses for the chest wall and internal mammary nodes, PTV1, and PTV of the supraclavicular nodes, PTV2, of 50 Gy were prescribed in 25 fractions. The plans were evaluated based on PTV1 and PTV2 coverage, homogeneity index (HI), conformity index, conformity number (CN), dose to organs at risk, NTCP, SCCP, EAR, number of monitors units, and beam delivery time.
resultsVMAT resulted in more homogeneous chest wall coverage than did IMRT. The percent volume of PTV1 that received the prescribed dose of VMRT and IMRT was 95.9 ± 1.2% and 94.5 ± 1.6%, respectively (p < 0.001). The HI was 0.11 ± 0.01 for VMAT and 0.12 ± 0.02 for IMRT, respectively (p = 0.001). The VMAT plan had better conformity (CN: 0.84 ± 0.02 vs. 0.78 ± 0.04, p < 0.001) in PTV compared with IMRT. As opposed to IMRT plans, VMAT delivered a lower mean dose to the ipsilateral lung (11.5 Gy vs 12.6 Gy) and heart (5.2 Gy vs 6.0 Gy) and significantly reduced the V
conclusionsCompared with IMRT, VMAT is the optimal technique for PMRT patients with left-sided breast cancer due to better target coverage, a lower dose delivered, NTCP, SCCP, and EAR to the ipsilateral lung and heart, similar doses delivered to the contralateral lung and breast, fewer monitor units and a shorter delivery time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.