Evidence map›Paper›PMID 34488705›Full record

ArticleBMC public health2021

HPV vaccination uptake and administration from 2006 to 2016 in a commercially insured population of the United States.

Vimalanand S Prabhu, Neha Bansal, Zhiwen Liu, Rodney Finalle, Martin Sénécal, Smita Kothari, Kemar Trowers, Evan Myers

Abstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vimalanand S PrabhuCenter for Observational and Real-World Evidence, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA. vimalanand.prabhu@merck.com.ORCID 0000-0003-1358-8846
Neha BansalComplete HEOR Solutions (CHEORS), North Wales, PA, USA.
Zhiwen LiuCenter for Observational and Real-World Evidence, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Rodney FinalleCenter for Observational and Real-World Evidence, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Martin SénécalComplete HEOR Solutions (CHEORS), North Wales, PA, USA.
Smita KothariCenter for Observational and Real-World Evidence, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Kemar TrowersCenter for Observational and Real-World Evidence, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA.
Evan MyersDivision of Women's Community and Population Health, Department of Obstetrics & Gynaecology, Duke University Medical Center, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman papillomavirus (HPV) infection can cause various cancers and can be prevented through vaccination. The American Cancer Society (ACS) has set an HPV vaccination completion target in 13-year-old children to 80% by 2026. While HPV vaccine coverage (proportion ever vaccinated) estimates are available, annual uptakes (proportion initiating vaccine in a year) in the United States (U.S.) are not well-known.

methodsWe analyzed MarketScan® claims database to assess HPV vaccination uptakes in the U.S. among the 9- to 26-year-olds in 2006-2016. The annual uptake was the ratio of the number of enrollees who had a first record of an HPV vaccine during the year, and the number of enrollees of similar age and sex that year.

resultsUptake was below 1% among children turning 9 and 10 years old during the year. Since 2009 among female and since 2013 among males, the annual uptake has been the highest in those turning 13 years old (19.7% among females and 17.6% among males in 2016). Catch-up vaccination among older adolescents and young adults increased after Advisory Committee for Immunization Practices (ACIP) recommendations, but eventually slowed down as more younger persons were vaccinated. Most young adolescents were vaccinated by pediatricians, whereas young adult women were predominantly vaccinated by obstetricians/gynecologists and young adult males by family physicians. While only about half of the adolescents had well-check visits, the majority of those who initiated HPV vaccination had one the same year.

conclusionContinued increase in uptake is needed to reach the ACS 2026 goals.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesAdolescentAdvisory CommitteesChildFemaleHumansMalePediatriciansUnited StatesVaccinationYoung AdultPapillomavirus VaccinesHPV vaccineHuman papillomavirusInsurance claims dataSex differencesTemporal trendsVaccination uptake

Identifiers

PMID34488705
PMCPMC8422649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.