ArticleBMC psychiatry2021
Investigating the impact of COVID-19 lockdown on adults with a recent history of recurrent major depressive disorder: a multi-Centre study using remote measurement technology.
Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Clinical Outcomes of Passive Sensors in Remote Monitoring: A Systematic Review.Sensors (Basel, Switzerland) · 2025Pooled it
- Association between the COVID-19 pandemic and psychiatric symptoms in people with preexisting obsessive-compulsive, eating, anxiety, and mood disorders: a systematic review and meta-analysis of before-after studies.Psychiatry and clinical neurosciences · 2023Pooled it
- Rethinking mental disorders in COVID-19: evidence from prepandemic longitudinal data.Current opinion in psychiatry · 2026Review
- Stigma and Relationship and Sexual Life in People with Severe Mental Disorders: A Systematic Review.Community mental health journal · 2026Article
- Impact of the COVID-19 pandemic on adults accessing specialist psychiatric care: A cross-sectional Canadian analysis.PloS one · 2026Article
- Review
- Biomarker-Guided Tailored Therapy in Major Depression.Advances in experimental medicine and biology · 2024Review
- Pre- and post-COVID 19 outbreak relationship between physical activity and depressive symptoms in Spanish adults with major depressive disorder: a secondary analysis of the RADAR-MDD cohort study.Frontiers in psychology · 2024Article
- Mental Health in the Post-Lockdown Scenario: A Scientometric Investigation of the Main Thematic Trends of Research.International journal of environmental research and public health · 2023Review
- Relationship between COVID-19 Pandemic Confinement and Worsening or Onset of Depressive Disorders.Brain sciences · 2023Review
- Impact of the COVID-19 pandemic on young people with and without pre-existing mental health problems.Scientific reports · 2023Article
- The Impact of COVID-19 Lockdown on Adults with Major Depressive Disorder from Catalonia: A Decentralized Longitudinal Study.International journal of environmental research and public health · 2023Article
- The experience of COVID-19 among people with depression: Impact on daily life and coping strategies.Journal of affective disorders · 2023Article
- Impact of COVID-19 pandemic on major depressive disorder in acute psychiatric inpatients.Frontiers in psychology · 2023Article
- Biopsychosocial Response to the COVID-19 Lockdown in People with Major Depressive Disorder and Multiple Sclerosis.Journal of clinical medicine · 2022Article
- Digital Phenotyping in Health Using Machine Learning Approaches: Scoping Review.JMIR bioinformatics and biotechnology · 2022Article
- Enhancing mHealth data collection applications with sensing capabilities.Frontiers in public health · 2022Article
- Exploring the Neuropsychiatric Sequalae of Perceived COVID-19 Exposure in College Students: A Pilot Digital Phenotyping Study.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
27 authors at 8 institutions in 7 countries.
Funding
Abstract
backgroundThe outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes a clinical illness Covid-19, has had a major impact on mental health globally. Those diagnosed with major depressive disorder (MDD) may be negatively impacted by the global pandemic due to social isolation, feelings of loneliness or lack of access to care. This study seeks to assess the impact of the 1st lockdown - pre-, during and post - in adults with a recent history of MDD across multiple centres.
methodsThis study is a secondary analysis of an on-going cohort study, RADAR-MDD project, a multi-centre study examining the use of remote measurement technology (RMT) in monitoring MDD. Self-reported questionnaire and passive data streams were analysed from participants who had joined the project prior to 1st December 2019 and had completed Patient Health and Self-esteem Questionnaires during the pandemic (n = 252). We used mixed models for repeated measures to estimate trajectories of depressive symptoms, self-esteem, and sleep duration.
resultsIn our sample of 252 participants, 48% (n = 121) had clinically relevant depressive symptoms shortly before the pandemic. For the sample as a whole, we found no evidence that depressive symptoms or self-esteem changed between pre-, during- and post-lockdown. However, we found evidence that mean sleep duration (in minutes) decreased significantly between during- and post- lockdown (- 12.16; 95% CI - 18.39 to - 5.92; p < 0.001). We also found that those experiencing clinically relevant depressive symptoms shortly before the pandemic showed a decrease in depressive symptoms, self-esteem and sleep duration between pre- and during- lockdown (interaction p = 0.047, p = 0.045 and p < 0.001, respectively) as compared to those who were not.
conclusionsWe identified changes in depressive symptoms and sleep duration over the course of lockdown, some of which varied according to whether participants were experiencing clinically relevant depressive symptoms shortly prior to the pandemic. However, the results of this study suggest that those with MDD do not experience a significant worsening in symptoms during the first months of the Covid - 19 pandemic.
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