Evidence map›Paper›PMID 34488669›Full record

ArticleBMC ophthalmology2021

Activation of quiescent polypoidal choroidal vasculopathy after membrane peeling vitrectomy for epiretinal membrane: a case report.

Yuelin Wang, Zhe Chen, Weihong Yu, Youxin Chen

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuelin Wang *Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China.
Zhe Chen *Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China.
Weihong YuDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China.
Youxin ChenDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China. chenyx@pumch.cn.ORCID http://orcid.org/0000-0002-7231-5058
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

The Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2018PT32029
6 · The paper itself

Abstract

backgroundRegular membrane peeling vitrectomy for epiretinal membrane (ERM) patients seldom causes large pigment epithelial detachment (PED). We presented an unusual case of the activation of quiescent polypoidal choroidal vasculopathy (PCV) after membrane peeling vitrectomy for ERM, with an uneven therapeutic process. CASE PRESENTATION: A 75-year-old female patient complained of metamorphopsia in her left eye for 2 years. Her best-corrected visual acuity was 20/160 with a moderate nuclear cataract. An irregular ERM and slight PED were shown in optical coherence tomography (OCT). No obvious orange-red lesion was detected. The patient underwent vitrectomy + ERM peeling + cataract surgery. After the operation, large PED emerged, and indocyanine green angiography (ICGA) confirmed PCV. Four monthly injections of intravitreal ranibizumab were administered, but PED persisted. After focal laser therapy targeted to the polyps combined with ranibizumab treatment, PED was absorbed.

conclusionsCareful evaluation for PCV before membrane peeling vitrectomy for ERM is important, as indolent PCV may be activated postoperatively. Anti-VEGF therapy accompanied by laser photocoagulation may be more effective for PCV polyps located away from the fovea.

Indexed as

Choroidal NeovascularizationEpiretinal MembranePolypsAgedFemaleFluorescein AngiographyHumansRanibizumabRetrospective StudiesTomography, Optical CoherenceVitrectomyRanibizumabCase reportEpiretinal membranePolypoidal choroidal vasculopathyVitrectomy

Identifiers

PMID34488669
PMCPMC8422602
OpenAlexW3196425468

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.