Evidence map›Paper›PMID 34488660›Full record

ArticleBMC infectious diseases2021

Perception of cure among leprosy patients post completion of multi-drug therapy.

Aleksandra Rosendo Dos Santos, Pãmela Rodrigues de Souza Silva, Letícia Gomes Costa, Peter Steinmann, Eliane Ignotti

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Aleksandra Rosendo Dos SantosHealth Sciences Graduation Program, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.
Pãmela Rodrigues de Souza SilvaFaculty of Nursing, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.
Letícia Gomes CostaFaculty of Health Sciences, University of the State of Mato Grosso (UNEMAT), Cáceres, Brazil.
Peter SteinmannSwiss Tropical and Public Health Institute (Swiss TPH), Socinstrasse 57, 4051, Basel, Switzerland. Peter.steinmann@swisstph.ch.ORCID http://orcid.org/0000-0003-4800-3019
Eliane IgnottiHealth Sciences Graduation Program, Federal University of Mato Grosso (UFMT), Cuiabá, Brazil.
Universidade do Estado de Mato Grosso · BRSwiss Tropical and Public Health Institute · CHUniversidade Federal de Mato Grosso · BR

Funding

FAPEMAT FAPEMAT/PPSUS 002/2013 - Proc 261606/2013
6 · The paper itself

Abstract

backgroundLeprosy is a treatable disease; however, the release from treatment after completion of multidrug therapy (MDT) often does not equal absence of health problems. Consequently, sequelae interfere with the patient's perception of cure. The objective of this study was to analyze the factors associated with the perception of not being healed among people treated for leprosy in a highly endemic area in Brazil.

methodA cross-sectional study of perceived cure of leprosy in the post-release from treatment period was conducted in Cáceres in the state of Mato Grosso, Brazil. The study included a total of 390 leprosy patients treated with MDT and released after completion of treatment from 1 January 2000 to 31 December 2017. The dependent variable was self-reported cure of leprosy; the independent variables included clinical, operational and socioeconomic variables.

resultsOut of the 390 former leprosy patients, 304 (77.9%) perceived themselves as cured and 86 (22.1%) considered themselves unhealed. Among the latter, 49 (57.0%) reported muscle weakness and joint pains. Individuals with complaints related to leprosy post-release from treatment had a 4.6 times higher chance to self-report as unhealed (OR 4.6; 95% CI 2.5-8.5). Patients with physical disabilities (PD) grade 1 and 2 at the time of the study had a 3.1 (OR 3.1; 95% CI 1.3-7.4) and 8.8 (OR 7.7; 95% CI 3.5-21.9) times higher likelihood to self-identify as unhealed, respectively.

conclusionAmong successfully treated leprosy patients, a quarter self-report as unhealed of the disease. The factors associated with the perception of being unhealed are PD and complaints related to leprosy in the post-release from treatment phase.

Indexed as

Leprostatic AgentsLeprosyBrazilCross-Sectional StudiesDrug Therapy, CombinationHumansPerceptionLeprostatic AgentsBrazilCureDisabilityLeprosyMultidrug therapy

Identifiers

PMID34488660
PMCPMC8419967
OpenAlexW3197056571

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.