Evidence map›Paper›PMID 34488442›Full record

ArticlemBio2021

Differential Effects of Prostaglandin D

Abhishek Kumar Verma, Jian Zheng, Matthias Mack, Florent Ginhoux, Stanley Perlman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Abhishek Kumar VermaDepartment of Microbiology and Immunology, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Jian ZhengDepartment of Microbiology and Immunology, University of Iowagrid.214572.7, Iowa City, Iowa, USA.
Matthias MackDepartment of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany.
Florent GinhouxShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Stanley PerlmanDepartment of Microbiology and Immunology, University of Iowagrid.214572.7, Iowa City, Iowa, USA.ORCID 0000-0003-4213-2354
University of Iowa · USAgency for Science, Technology and Research · SGUniversity Hospital Regensburg · DE

Funding

Role of microglia in MHV-induced demyelinationR01NS036592 · NINDS · UNIVERSITY OF IOWA · PI PERLMAN, STANLEY · 1997 to 2021
$6.0M
HHS | U.S. Public Health Service (USPHS) RO1 NS36592National Multiple Sclerosis Society (National MS Society) RG 5340-A-7NINDS NIH HHS R01 NS036592
6 · The paper itself

Abstract

Microglia and macrophages initiate and orchestrate the innate immune response to central nervous system (CNS) virus infections. Microglia initiate neurotropic coronavirus clearance from the CNS, but the role of infiltrating macrophages is not well understood. Here, using mice lacking cell-specific expression of DP1, the receptor for prostaglandin D

Indexed as

AnimalsEncephalitisMacrophagesMiceMicrogliaMurine hepatitis virusPhagocytosisProstaglandin D2Signal TransductionTranscription Factor DP1Prostaglandin D2Transcription Factor DP1coronavirusencephalitismacrophagemicrogliamouse hepatitis virus (MHV)Ms4a3-crePGD2/DP1 axisphagocytosis

Identifiers

PMID34488442
PMCPMC8546556
OpenAlexW3197649500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.