Evidence map›Paper›PMID 34488302›Full record

ArticleJournal of movement disorders2021

Focused Vibrotactile Stimulation with Cueing Effect on Freezing of Gait in Parkinson's Disease: Two Case Reports.

Xiu Sheng Tan, Floyd Pierres, Alex Dallman-Porter, William Hardie-Brown, Kyum-Yil Kwon

Registry-linked trialOpen access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of movement disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06174948 (The Use of the CUE1/CUE1+ Device in People With Idiopathic Parkinson's Disease and Related Disorders), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06174948 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Use of the CUE1/CUE1+ Device in People With Idiopathic Parkinson's Disease and Related Disorders: A Feasibility Study

TypeinterventionalSponsorQueen Mary University of LondonRan2024 to 2025Enrolled70ConditionsParkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, Different Types of Tremor Including Essential Tremor, DystoniaArmsCUE1 non-invasive device, CUE1+ device active vs sham CUE1+ device
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xiu Sheng TanSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Floyd PierresCharco Neurotech Ltd., London, United Kingdom.
Alex Dallman-PorterCharco Neurotech Ltd., London, United Kingdom.
William Hardie-BrownCharco Neurotech Ltd., London, United Kingdom.
Kyum-Yil KwonDepartment of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
Peterborough City Hospital · GBSoonchunhyang University Hospital Seoul · KRUniversity of Cambridge · GB

Funding

Soonchunhyang University 20200501
6 · The paper itself

Abstract

Freezing of gait (FOG) is a common occurrence in patients with Parkinson's disease (PD) that leads to significant limitations in mobility and increases risk of falls. Focused vibrotactile stimulation and cueing are two methods used to alleviate motor symptoms, including FOG, in patients with PD. While effective on their own, the effect of combining both focused vibrotactile stimulation and cueing has yet to be investigated. Two patients, both with a history of PD, suffered from frequent FOG episodes that failed to respond adequately to medication. A novel vibrotactile stimulation device that delivered rhythmic kinesthetic stimuli onto the sternum successfully reduced FOG episodes in both patients and drastically improved their mobility as measured by the Timed Up and Go test. We found that a combination of focused vibrotactile stimulation and cueing was effective in reducing FOG episodes in two patients with PD. Further well-designed prospective studies are needed to confirm our observations.

Indexed as

CueingFreezing of gaitParkinson’s diseaseVibrotactile stimulation

Identifiers

PMID34488302
PMCPMC8490196
OpenAlexW3196347976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.