ArticleBiomedical physics & engineering express2021
Study of optical reflectors for a 100ps coincidence time resolution TOF-PET detector design.
Article in Biomedical physics & engineering express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 25 citations in OpenAlex.
- Current Status of Cherenkov-Based Gamma Detectors for TOF-PET and Proton Range Verification.IEEE transactions on radiation and plasma medical sciences · 2026Article
- A new design to improve time resolution in a time of flight brain PET using dual layer offset scintillator crystals.Scientific reports · 2025Article
- Comprehensive simulation study and preliminary results on various shapes of nanopatterns for light extraction improvement in scintillation crystal.Biomedical engineering letters · 2025Article
- Design and proof of concept of a double-panel TOF-PET system.EJNMMI physics · 2024Article
- Colored reflectors to improve coincidence timing resolution of BGO-based time-of-flight PET detectors.Physics in medicine and biology · 2023Article
- Advances in Detector Instrumentation for PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Review
- Investigation of Electronic Signal Processing Chains for a Prototype TOF-PET System With 100-ps Coincidence Time Resolution.IEEE transactions on radiation and plasma medical sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Positron Emission Tomography (PET) reconstructed image signal-to-noise ratio (SNR) can be improved by including the 511 keV photon pair coincidence time-of-flight (TOF) information. The degree of SNR improvement from this TOF capability depends on the coincidence time resolution (CTR) of the PET system, which is essentially the variation in photon arrival time differences over all coincident photon pairs detected for a point positron source placed at the system center. The CTR is determined by several factors including the intrinsic properties of the scintillation crystals and photodetectors, crystal-to-photodetector coupling configurations, reflective materials, and the electronic readout configuration scheme. The goal of the present work is to build a novel TOF-PET system with 100 picoseconds (ps) CTR, which provides an additional factor of 1.5-2.0 improvement in reconstructed image SNR compared to state-of-the-art TOF-PET systems which achieve 225-400 ps CTR. A critical parameter to understand is the optical reflector's influence on scintillation light collection and transit time variations to the photodetector. To study the effects of the reflector covering the scintillation crystal element on CTR, we have tested the performance of four different reflector materials: Enhanced Specular Reflector (ESR) -coupled with air or optical grease to the scintillator; Teflon tape; BaSO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.