Evidence map›Paper›PMID 34488078›Full record

ArticleDrug and alcohol dependence2021

Gender differences in the prevalence of heroin and opioid analgesic misuse in the United States, 2015-2019.

R Kathryn McHugh, Minh D Nguyen, Elena H Chartoff, Dawn E Sugarman, Shelly F Greenfield

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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  17. Access to Services for Pregnant People With Opioid Use Disorder in Jails in the United States.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

R Kathryn McHughMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, United States; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, United States. Electronic address: kmchugh@mclean.harvard.edu.
Minh D NguyenMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, United States.
Elena H ChartoffMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, United States; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, United States.
Dawn E SugarmanMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, United States; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, United States.
Shelly F GreenfieldMcLean Hospital, 115 Mill Street, Belmont, MA, 02478, United States; Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, United States.
Harvard University · USMcLean Hospital · US

Funding

Affective and Inflammatory Reactivity to Pain in Opioid Use DisorderR01DA045632 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2019 to 2022
$1.5M
Increasing Women's Engagement in Medication Treatment for Opioid Use Disorder through Digital InterventionK23DA050780 · NIDA · MCLEAN HOSPITAL · PI SUGARMAN, DAWN E · 2020 to 2024
$938k
Sex and Gender Differences in Response to Behavioral Strategies for Reducing Stress ReactivityR21DA046937 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2018 to 2019
$556k
NIDA NIH HHS K23 DA050780NIDA NIH HHS R01 DA045632NIDA NIH HHS R21 DA046937
6 · The paper itself

Abstract

objectivesGender differences in the prevalence of opioid misuse continue to evolve and have not been well characterized in recent years. Our objective was to investigate gender differences in the prevalence of opioid misuse and use disorder in the US over the 5-year period from 2015 to 2019.

methodsWe used annual survey data from the 2015-2019 National Survey on Drug Use and Health to estimate gender differences in the prevalence of opioid misuse. We examined past-year opioid analgesic misuse initiation, opioid analgesic misuse, heroin use, opioid analgesic use disorder and heroin use disorder. Logistic regression models were used to test gender differences, adjusting for sociodemographic variables.

resultsIn adjusted analyses, women had higher odds of having initiated opioid analgesic misuse in the past year compared to men. In contrast, men had higher odds of misuse of opioid analgesics, heroin use, and an opioid analgesic or heroin use disorder.

conclusionsAlthough opioid misuse has historically been more prevalent in men, the gender difference in opioid analgesic misuse continues to narrow, with more women initiating misuse than men including higher rates of misuse in adolescent girls. Heroin use continues to be approximately twice as common in men as women.

Indexed as

Opioid-Related DisordersPrescription Drug MisuseAdolescentAnalgesics, OpioidFemaleHeroinHumansMalePrevalenceSex FactorsUnited StatesAnalgesics, OpioidHeroinGender differencesHeroin misuseOpioid misuseOpioid use disorderWomen

Identifiers

PMID34488078
PMCPMC8516063
OpenAlexW3198511992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.