ArticlePediatric pulmonology2021
Chest X-ray lung imaging features in pediatric COVID-19 and comparison with viral lower respiratory infections in young children.
Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Pediatric SARS-CoV-2 long term outcomes study: chest radiographic and computed tomography findings at baseline.Pediatric radiology · 2026Article
- Impact of universal nirsevimab prophylaxis on clinical and ultrasound presentations of lower respiratory tract infections in hospitalized pediatric patients.European journal of pediatrics · 2025Observational
- SARS-CoV-2 paediatric chest X-ray findings during the Omicron variant wave.Southern African journal of infectious diseases · 2025Article
- Radiographic patterns and severity scoring of COVID-19 pneumonia in children: a retrospective study.BMC medical imaging · 2023Article
- Developing artificial intelligence technology for pediatric pulmonology: Lessons from COVID-19.Pediatric pulmonology · 2022Article
- Machine learning early prediction of respiratory syncytial virus in pediatric hospitalized patients.Frontiers in pediatrics · 2022Article
- Chest X-ray lung imaging features in pediatric COVID-19 and comparison with viral lower respiratory infections in young children.Pediatric pulmonology · 2021Article
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
rationaleChest radiography (CXR) is a noninvasive imaging approach commonly used to evaluate lower respiratory tract infections (LRTIs) in children. However, the specific imaging patterns of pediatric coronavirus disease 2019 (COVID-19) on CXR, their relationship to clinical outcomes, and the possible differences from LRTIs caused by other viruses in children remain to be defined.
methodsThis is a cross-sectional study of patients seen at a pediatric hospital with polymerase chain reaction (PCR)-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 95). Patients were subdivided in infants (0-2 years, n = 27), children (3-10 years, n = 27), and adolescents (11-19 years, n = 41). A sample of young children (0-2 years, n = 68) with other viral lower respiratory infections (LRTI) was included to compare their CXR features with the subset of infants (0-2 years) with COVID-19.
resultsForty-five percent of pediatric patients with COVID-19 were hospitalized and 20% required admission to intensive care unit (ICU). The most common abnormalities identified were ground-glass opacifications (GGO)/consolidations (35%) and increased peribronchial markings/cuffing (33%). GGO/consolidations were more common in older individuals and perihilar markings were more common in younger subjects. Subjects requiring hospitalization or ICU admission had significantly more GGO/consolidations in CXR (p < .05). Typical CXR features of pediatric viral LRTI (e.g., hyperinflation) were more common in non-COVID-19 viral LRTI cases than in COVID-19 cases (p < .05).
conclusionsCXR may be a complemental exam in the evaluation of moderate or severe pediatric COVID-19 cases. The severity of GGO/consolidations seen in CXR is predictive of clinically relevant outcomes. Hyperinflation could potentially aid clinical assessment in distinguishing COVID-19 from other types of viral LRTI in young children.
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