ArticleHuman brain mapping2021
Spatiotemporal changes in diffusivity and anisotropy in fetal brain tractography.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Diffusion Tensor Imaging of Fetuses With Congenital Diaphragmatic Hernia.Prenatal diagnosis · 2025Article
- Regional Changes in the Fetal Telencephalic Wall Diffusion Metrics Across Late Second and Third Trimesters.Human brain mapping · 2025Article
- A detailed spatiotemporal atlas of the white matter tracts for the fetal brain.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Perinatal development of structural thalamocortical connectivity.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- HAITCH: A framework for distortion and motion correction in fetal multi-shell diffusion-weighted MRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Ex vivo Magnetic Resonance Imaging of the Human Fetal Brain.Developmental neuroscience · 2025Review
- Anatomically constrained tractography of the fetal brain.NeuroImage · 2024Article
- Advances in Fetal Brain Imaging.Magnetic resonance imaging clinics of North America · 2024Review
- Development of the Fetal Brain Corticocortical Structural Network during the Second-to-Third Trimester Based on Diffusion MRI.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Characterizing Large-Scale Human Circuit Development with In Vivo Neuroimaging.Cold Spring Harbor perspectives in biology · 2024Review
- A detailed spatio-temporal atlas of the white matter tracts for the fetal brain.bioRxiv : the preprint server for biology · 2024Article
- Characterizing microstructural development in the fetal brain using diffusion MRI from 23 to 36 weeks of gestation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- DTI of Opioid-Exposed Fetuses Using ComBat Harmonization: A Bi-Institutional Study.AJNR. American journal of neuroradiology · 2023Article
- Article
- Fetal MRI at 3 T: Principles to Optimize Success.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023Article
- Detailed anatomic segmentations of a fetal brain diffusion tensor imaging atlas between 23 and 30 weeks of gestation.Human brain mapping · 2023Article
- Early structural connectivity within the sensorimotor network: Deviations related to prematurity and association to neurodevelopmental outcome.Frontiers in neuroscience · 2022Article
- Spatiotemporal changes in diffusivity and anisotropy in fetal brain tractography.Human brain mapping · 2021Article
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9 authors.
Funding
Abstract
Population averaged diffusion atlases can be utilized to characterize complex microstructural changes with less bias than data from individual subjects. In this study, a fetal diffusion tensor imaging (DTI) atlas was used to investigate tract-based changes in anisotropy and diffusivity in vivo from 23 to 38 weeks of gestational age (GA). Healthy pregnant volunteers with typically developing fetuses were imaged at 3 T. Acquisition included structural images processed with a super-resolution algorithm and DTI images processed with a motion-tracked slice-to-volume registration algorithm. The DTI from individual subjects were used to generate 16 templates, each specific to a week of GA; this was accomplished by means of a tensor-to-tensor diffeomorphic deformable registration method integrated with kernel regression in age. Deterministic tractography was performed to outline the forceps major, forceps minor, bilateral corticospinal tracts (CST), bilateral inferior fronto-occipital fasciculus (IFOF), bilateral inferior longitudinal fasciculus (ILF), and bilateral uncinate fasciculus (UF). The mean fractional anisotropy (FA) and mean diffusivity (MD) was recorded for all tracts. For a subset of tracts (forceps major, CST, and IFOF) we manually divided the tractograms into anatomy conforming segments to evaluate within-tract changes. We found tract-specific, nonlinear, age related changes in FA and MD. Early in gestation, these trends appear to be dominated by cytoarchitectonic changes in the transient white matter fetal zones while later in gestation, trends conforming to the progression of myelination were observed. We also observed significant (local) heterogeneity in within-tract developmental trajectories for the CST, IFOF, and forceps major.
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