Evidence map›Paper›PMID 34487368›Full record

ArticleAlcoholism, clinical and experimental research2021

COVID-19 pandemic and methanol poisoning outbreak in Iranian children and adolescents: A data linkage study.

Seyed Amirhosein Mahdavi, Ali-Asghar Kolahi, Maryam Akhgari, Farzad Gheshlaghi, Narges Gholami, Mohammad Moshiri, Neda Mohtasham, Sara Ebrahimi, Pardis Ziaeefar, Rebecca McDonald and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Suicide Risk Factors in High School Students.International journal of environmental research and public health · 2024
    Article
  4. Review
  5. Observational
  6. Article
  7. Review
  8. Childhood Poisoning During the COVID-19 Pandemic.Turkish archives of pediatrics · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 2 countries.

Seyed Amirhosein MahdaviLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.ORCID 0000-0001-6057-0302
Ali-Asghar KolahiSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-0178-3732
Maryam AkhgariLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.ORCID 0000-0002-4126-3398
Farzad GheshlaghiDepartment of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0002-8972-7366
Narges GholamiDepartment of Pediatrics, School of Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3138-0224
Mohammad MoshiriMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0003-0389-2270
Neda MohtashamDepartment of Pediatric Clinical Toxicology, Abuzar's Children Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.ORCID 0000-0001-8187-1518
Sara EbrahimiSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-7273-8352
Pardis ZiaeefarSchool of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-1074-1518
Rebecca McDonaldNational Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-3373-4943
Basak TasNational Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0002-3137-7631
Amir Mohammad KazemifarDepartment of Internal Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0002-4219-083X
Alireza AmirabadizadehCardiovascular Disease Research Center, Birjand University of Medical Sciences, South Khorasan, Iran.ORCID 0000-0002-6945-5148
Mohammadreza GhadirzadehLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.ORCID 0000-0003-0061-6174
Farkhondeh JamshidiDepartment of Forensic Medicine and Social Determinant of Health Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.ORCID 0000-0003-2439-617X
Bita DadpourMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID 0000-0001-6004-0344
Seyed Davood MirtorabiLegal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.ORCID 0000-0001-5175-9736
Fariba FarnaghiDepartment of Pediatrics, School of Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3831-8052
Nasim ZamaniSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-2091-0197
Hossein Hassanian-MoghaddamSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-4370-0544
Shahid Beheshti University of Medical Sciences · IRIranian Legal Medicine Organization · IRAhvaz Jundishapur University of Medical Sciences · IRKing's College London · GBMashhad University of Medical Sciences · IRBirjand University of Medical Sciences · IRIsfahan University of Medical Sciences · IRQazvin University of Medical Sciences · IR

Funding

Shahid Beheshti University of Medical Sciences 24276
6 · The paper itself

Abstract

backgroundDuring the first wave of COVID-19, many Iranians were poisoned by ingesting hand sanitizers and/or alcoholic beverages to avoid viral infection. To assess whether the COVID-19 pandemic resulted in an increased prevalence of accidental hand sanitizer/alcoholic beverage exposure in children and adolescents, we compared pediatric hospitalization rates during COVID-19 and the previous year. For poisoning admissions during COVID-19, we also evaluated the cause by age and clinical outcomes.

methodsThis retrospective data linkage study evaluated data from the Legal Medicine Organization (reporting mortalities) and hospitalization data from nine toxicology referral centers for alcohol-poisoned patients (age 0 to 18 years) for the study period (February 23 to June 22, 2020) and the pre-COVID-19 reference period (same dates in 2019).

resultsHospitalization rates due to ethanol and methanol exposure were significantly higher in 2020 (n = 375) than 2019 (n = 202; OR [95% CI] 1.9 [1.6, 2.2], p < 0.001). During COVID-19, in patients ≤15 years, the odds of intoxication from hand sanitizers were significantly higher than from alcoholic beverages, while in 15- to 18-year-olds, alcoholic beverage exposure was 6.7 times more common (95% CI 2.8, 16.1, p < 0.001). Of 375 children/adolescents hospitalized for alcoholic beverage and hand sanitizer exposure in 2020, six did not survive. The odds of fatal outcome were seven times higher in 15- to 18-year-olds (OR (95% CI) 7.0 (2.4, 20.1); p < 0.001).

conclusionThe Iranian methanol poisoning outbreak during the first wave of COVID-19 was associated with significantly increased hospitalization rates among children and adolescents-including at least six pediatric in-hospital deaths from poisoning. Public awareness needs to be raised of the risks associated with ingesting alcoholic hand sanitizers.

Indexed as

AdolescentAlcoholic BeveragesAlcoholic IntoxicationChildChild, PreschoolCOVID-19FemaleHand SanitizersHospitalizationHumansInfantInformation Storage and RetrievalIranMaleMethanolRetrospective StudiesHand SanitizersMethanolCOVID-19hand sanitizersmethanoloutbreakpediatricpoisoning

Identifiers

PMID34487368
PMCPMC8653331
OpenAlexW3196473490

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.