Trial reportJournal of neuro-oncology2021
eHealth cognitive rehabilitation for brain tumor patients: results of a randomized controlled trial.
Trial report in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Impact of Cognitive Rehabilitation on Cognitive and Functional Outcomes in Adult Cancer Survivors: A Systematic Review.Seminars in oncology nursing · 2024Pooled it
- A systematic review of cognitive telerehabilitation in patients with cognitive dysfunction.Frontiers in neurology · 2024Pooled it
- Repeated awake surgery and quality of life in patients with diffuse glioma: a systematic review and meta-analysis.Neurosurgical review · 2023Pooled it
- A systematic review of cognitive interventions for adult patients with brain tumours.Cancer medicine · 2023Pooled it
- Web-based psychoeducational interventions for managing cognitive impairment-a systematic review.Frontiers in neurology · 2023Pooled it
- Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation.The Cochrane database of systematic reviews · 2022Pooled it
- Early mobilization in postoperative glioma patients real world impact on recovery and long term prognosis.Scientific reports · 2025Trial
- Telehealth group Cognitive-Behavioral Therapy for Insomnia (CBT-I) in primary brain tumor: Primary outcomes from a single-arm phase II feasibility and proof-of-concept trial.Neuro-oncology · 2024Trial
- Methodology of analysis of cognitive impairment in longitudinal randomized clinical trials in oncology: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Application of multidimensional cognitive training in the early postoperative period for glioma patients with cognitive impairment.Journal of neuro-oncology · 2026Article
- Tele-cognitive rehabilitation for adult lower-grade glioma: An interim prospective pilot feasibility study.Neuro-oncology practice · 2026Article
- Feasibility of a novel web-based neuropsychological rehabilitation programme for stroke patients.Journal of rehabilitation medicine · 2025Article
- Cognitive Rehabilitation of Brain Tumor Survivors: A Systematic Review.Brain tumor research and treatment · 2025Review
- Efficacy of hybrid remote neuropsychological rehabilitation on cognitive complaints in post-therapeutic lower-grade glioma: the FREEDOME randomized study protocol.Frontiers in psychology · 2025Article
- Article
- Treatment Options for IDH-Mutant Malignant Gliomas.Current treatment options in oncology · 2024Review
- Systematic review and meta-analysis of standalone digital interventions for cognitive symptoms in people without dementia.NPJ digital medicine · 2024Article
- Inequalities in access to neuro-oncology supportive care and rehabilitation: A survey of healthcare professionals' perspectives.Neuro-oncology practice · 2024Article
- Cancer Patients' Perspectives and Requirements of Digital Health Technologies: A Scoping Literature Review.Cancers · 2024Article
- Cognitive functioning in untreated glioma patients: The limited predictive value of clinical variables.Neuro-oncology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundEvidence-based cognitive rehabilitation programs for brain tumor patients are not widely available, despite the high need. We aimed to evaluate the effects of a tablet-based cognitive rehabilitation program on cognitive performance, cognitive complaints, fatigue, and psychological distress in primary brain tumor patients following neurosurgery. Also, attrition, adherence and patient satisfaction with the program were evaluated.
methodsAdults with presumed low-grade glioma and meningioma were recruited before surgery. Three months thereafter, participants were allocated to the intervention group or waiting-list control group using minimization. The 10-week eHealth app ReMind, based on the effective face-to-face intervention, consisted of psychoeducation, strategy-training and attention retraining. Performance-based cognitive outcomes and patient-reported outcomes were assessed before surgery and 3, 6 and 12 months thereafter. Mean scores, percentages of cognitively impaired individuals and reliable change indices (RCIs) were compared between groups.
resultsSixty-two out of 183 eligible patients were randomized. Of the people who declined, 56% reported that participation would to be too burdensome. All participants found a tablet-app suitable for delivery of cognitive rehabilitation and 90% rated the program as "good" or "excellent". Performance-based cognitive outcomes and patient-reported outcomes did not significantly differ in group means over time nor RCIs between the intervention (final n = 20) and control group (final n = 25).
conclusionsRecruitment at this early stage was difficult, resulting in limited statistical power. No significant effects were demonstrated, while adherence and satisfaction with the eHealth program were good. In clinical practice, ReMind may be helpful, if timing would be adapted to patients' needs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.