Evidence map›Paper›PMID 34487308›Full record

ArticleStem cell reviews and reports2021

Oxidative Stress Enhances Autophagy-Mediated Death Of Stem Cells Through Erk1/2 Signaling Pathway - Implications For Neurotransplantations.

Ravi Prakash, Eram Fauzia, Abu Junaid Siddiqui, Santosh Kumar Yadav, Neha Kumari, Atin Singhai, Mohsin Ali Khan, Miroslaw Janowski, Sujit Kumar Bhutia, Syed Shadab Raza

Abstract read
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In one paragraph

Article in Stem cell reviews and reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Liproxstatin-1 Protects SH-SY5Y Cells by Inhibiting HInternational journal of molecular sciences · 2025
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  10. Mitochondria in Cell-Based Therapy for Stroke.Antioxidants (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Number 2 Feibi Recipe Inhibits HFrontiers in pharmacology · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ravi PrakashLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India.
Eram FauziaLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India.
Abu Junaid SiddiquiLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India.
Santosh Kumar YadavLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India.
Neha KumariLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India.
Atin SinghaiDepartment of Pathology, King George's Medical University, Lucknow, 226020, India.
Mohsin Ali KhanEra University, Lucknow, 226003, India.
Miroslaw JanowskiCenter for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, University of Maryland Baltimore, Baltimore, MD, 21201-1595, USA.
Sujit Kumar BhutiaDepartment of Life Science, National Institute of Technology, Rourkela, 769008, India.
Syed Shadab RazaLaboratory for Stem Cell & Restorative Neurology, Department of Biotechnology, Era's Lucknow Medical College Hospital, Era University, Sarfarazganj, Lucknow, 226003, India. drshadab@erauniversity.in.ORCID http://orcid.org/0000-0002-6147-9399
Era's Lucknow Medical College and Hospital · INInstitute for Stem Cell Biology and Regenerative Medicine · INKing George's Medical University · INNational Institute of Technology Rourkela · INUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapies are becoming increasingly popular solutions for neurological disorders. However, there is a lower survival rate of these cells after transplantation. Oxidative stress is linked to brain damage, and it may also impact transplanted stem cells. To better understand how transplanted cells respond to oxidative stress, the current study used H

Indexed as

Hydrogen PeroxideMesenchymal Stem CellsAutophagyHumansOxidative StressSignal TransductionHydrogen PeroxideAutophagyErk1/2H2O2Oxidative StressStroke

Identifiers

PMID34487308
OpenAlexW3197691195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.