Evidence map›Paper›PMID 34487266›Full record

ReviewWorld journal of microbiology & biotechnology2021

Recent advances in the enzymatic production and applications of xylooligosaccharides.

Caio Cesar de Mello Capetti, Milena Moreira Vacilotto, Andrei Nicoli Gebieluca Dabul, Ana Gabriela Veiga Sepulchro, Vanessa Oliveira Arnoldi Pellegrini, Igor Polikarpov

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Enzymatic production of prebiotic xylooligosaccharides.World journal of microbiology & biotechnology · 2026
    Review
  3. Enzymatic Production of Prebiotic Xylooligosaccharides Using aJournal of agricultural and food chemistry · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Understanding the probiotic health benefits ofFrontiers in microbiology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Caio Cesar de Mello Capetti *São Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil.
Milena Moreira Vacilotto *São Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil.
Andrei Nicoli Gebieluca DabulSão Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil.
Ana Gabriela Veiga SepulchroSão Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil.
Vanessa Oliveira Arnoldi PellegriniSão Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil.
Igor PolikarpovSão Carlos Institute of Physics, University of São Paulo, 400 Trabalhador São-carlense Ave, São Carlos, SP, 13566-590, Brazil. ipolikarpov@ifsc.usp.br.ORCID http://orcid.org/0000-0001-9496-4174
Universidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 303988/2016-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.601517/2021-00Fundação de Amparo à Pesquisa do Estado de São Paulo 15/13684-0
6 · The paper itself

Abstract

The majority of lignocellulosic biomass on the planet originates from plant cell walls, which are complex structures build up mainly by cellulose, hemicellulose and lignin. The largest part of hemicellulose, xylan, is a polymer with a β-(1→4)-linked xylose residues backbone decorated with α-D-glucopyranosyl uronic acids and/or L-arabinofuranose residues. Xylan is the second most abundant biopolymer in nature, which can be sustainably and efficiently degraded into decorated and undecorated xylooligosaccharides (XOS) using combinations of thermochemical pretreatments and enzymatic hydrolyses, that have broad applications in the food, feed, pharmaceutical and cosmetic industries. Endo-xylanases from different complex carbohydrate-active enzyme (CAZyme) families can be used to cleave the backbone of arabino(glucurono)xylans and xylooligosaccharides and degrade them into short XOS. It has been shown that XOS with a low degree of polymerization have enhanced prebiotic effects conferring health benefits to humans and animals. In this review we describe recent advances in the enzymatic production of XOS from lignocellulosic biomass arabino- and glucuronoxylans and their applications as food and feed additives and health-promoting ingredients. Comparative advantages of xylanases from different CAZy families in XOS production are discussed and potential health benefits of different XOS are presented.

Indexed as

BiocatalysisBiotechnologyEndo-1,4-beta XylanasesGlucuronatesHydrolysisOligosaccharidesXylansEndo-1,4-beta XylanasesGlucuronatesOligosaccharidesXylansxylooligosaccharideBiomassEnzymatic hydrolysisXylanasesXylooligosaccharides

Identifiers

PMID34487266
OpenAlexW3196419724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.