Evidence map›Paper›PMID 34487251›Full record

ArticleJournal of patient-reported outcomes2021

Translation and validation of the Urdu version of the European organization for research and treatment of cancer core quality of life questionnaire (EORTC QLQ-C30) and brain module (QLQ-BN20) in primary brain tumor patients.

Nida Zahid, Russell Seth Martins, Wajeeha Zahid, Wardah Khalid, Iqbal Azam, Shireen Shehzad Bhamani, Nargis Asad, Khabir Ahmad, Adnan Abdul Jabbar, Muhammad Shahzad Shamim and 4 more

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Article in Journal of patient-reported outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

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8citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Nida ZahidDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan. nida.zahid@aku.edu.ORCID http://orcid.org/0000-0001-8812-9463
Russell Seth MartinsMedical College, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Wajeeha ZahidDepartment of Community Health Sciences, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Wardah KhalidDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Iqbal AzamDepartment of Community Health Sciences, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Shireen Shehzad BhamaniSchool of Nursing and Midwifery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Nargis AsadDepartment of Psychiatry, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Khabir AhmadDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Adnan Abdul JabbarDepartment of Oncology, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Muhammad Shahzad ShamimDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Rashid Jooma KhanDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Gohar JavedDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Ehsan BariDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Syed Ather EnamDepartment of Surgery, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.

Funding

Aga Khan University Seed Money Grant PF98/0417
6 · The paper itself

Abstract

introductionThis study translated and validated the Urdu version of the European Organization for Research and Treatment of Cancer Quality of Life (QoL) Questionnaire (EORTC QLQ-C30) and Brain Module (QLQ-BN20) amongst patients with primary brain tumors (PBT) in Pakistan, and assessed the correlation of QoL with resilience, depression, and anxiety.

methodsTranslation of the EORTC QLQ-C30 and QLQ-BN20 was performed as per EORTC guidelines. A survey comprising of Urdu translations of EORTC QLQ-C30, QLQ-BN20, Wagnild and Young Resilience Scale (RS-14) and Hospital Anxiety and Depression Scale was administered to patients with PBT at a tertiary care hospital in Pakistan. Reliability (via Cronbach alpha), content validity index (CVI) scores, construct validity, and inter-scale correlations were assessed.

resultsOur sample consisted of 250 patients with PBT, most commonly glioma (46.8%) and meningioma (21.2%). All patients were able to understand the Urdu translations. The Cronbach alphas for the QLQ-C30 and the QLQ-BN20 were 0.860 and 0.880, respectively. The CVI scores for clarity and relevance were high for both the EORTC QLQ-C30 (0.98 and 0.96, respectively) and the QLQ-BN20 tool (0.81 and 0.95, respectively). The global QoL domain (EORTC QLQ-C30) showed significant positive correlations with resilience (r = 0.422), and significant negative correlations with depression (r =  - 0.541) and anxiety (r =  - 0.502). Strong inter-scale correlations were observed between physical functioning and insomnia (r =  - 0.690) and role functioning and insomnia (r =  - 0.641).

conclusionOur study confirms the Urdu versions of the EORTC QLQ-C30 and QLQ-BN20 as valid clinical tools for the measurement of QoL in primary brain tumors patients within the cultural and socioeconomic context of Pakistan.

Indexed as

CorrelationDepressionPrimary brain tumorQuality of lifeReliabilityResilienceUrduValidity

Identifiers

PMID34487251
PMCPMC8421474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.