SynthesisClinical oral investigations2021
Quantitative sensory testing in patients with the muscle pain subtype of temporomandibular disorder: a systemic review and meta-analysis.
Synthesis in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07514208 (Pericranial and General Sensitivity in Patients With Primary Headache), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pericranial and General Sensitivity in Patients With Primary Headache: a Multicenter Case-control Study
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pain mechanisms in complex regional pain syndrome: a systematic review and meta-analysis of quantitative sensory testing outcomes.Journal of orthopaedic surgery and research · 2023Pooled it
- Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls.Journal of oral rehabilitation · 2026Article
- Masticatory myalgia to headache-like secondary hypersensitivity induces gene plasticity at dura mater.The journal of headache and pain · 2026Article
- Pharmacological Interventions in the Management of Temporomandibular Disorders: A Systematic Review and Meta-analysis.Acta stomatologica Croatica · 2026Article
- How does temporomandibular dysfunction affect neck awareness, cervical sensorimotor performance, and pain sensitivity?Revista da Associacao Medica Brasileira (1992) · 2026Observational
- Central Sensitization and Somatization in Adults with Temporomandibular Disorders: A Prospective Study.Journal of pharmacy & bioallied sciences · 2025Article
- Defining Effect Size Standards in Temporomandibular Joint and Masticatory Muscle Research.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Prevalence of central sensitization and somatization in adults with temporomandibular disorders-a prospective observational study.Journal of oral & facial pain and headache · 2024Observational
- Pain sensitization and pain-related psychological factors in patients with temporomandibular disorders: an observational cross-sectional study.Clinical oral investigations · 2024Observational
- Influence of psychometric and sleep quality features on painful mechanical sensitivity and pain modulation in patients with temporomandibular disorders.Clinical oral investigations · 2024Article
- Pain symptoms are associated with two-point discrimination threshold in patients with temporomandibular disorders.Clinical oral investigations · 2024Article
- Feasibility and acceptability of remote administration of the cold pressor test.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review.International journal of molecular sciences · 2022Review
- Temporal Summation and Aftersensations of Second Pain in Women with Myofascial Temporomandibular Disorder Differ by Presence of Temporomandibular Joint Pain.Journal of pain research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectivesThis meta-analysis aimed to evaluate quantitative sensory testing (QST) evidence for pain processing in patients with the muscle pain subtype of temporomandibular disorders (mTMD). MATERIALS AND
methodsA comprehensive systematic electronic search strategy was performed in online literature databases. All full-text observational studies published up to July 2021 with the aim of investigating pain sensitization in humans with mTMD using QST measures were eligible for inclusion. Meta-analysis of QST data was performed using a random effects model, which included results comparing patients with mTMD to healthy controls, and standard mean difference (SMD) results were analyzed.
resultsTwelve studies with 732 participants (371 patients with mTMD and 361 healthy controls) were analyzed following screening and quality appraisal. Compared with healthy controls, patients with mTMD had significantly lower pressure pain threshold (SMD - 1.10, 95% confidence interval [CI] - 1.52 to - 0.68) with high heterogeneity (Tau
conclusionsThe study results suggest that the pain processing of deep tissues is likely sensitized in mTMD and calls for more QST studies with standard procedures to reduce inter-study heterogeneity. CLINICAL RELEVANCE: The major findings of this meta-analysis support using PPT to examine the pain processing in patients with mTMD in clinical scenario.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.