Evidence map›Paper›PMID 34487108›Full record

ArticleActa bio-medica : Atenei Parmensis2021

A Pilot study on correlation between Zinc and Magnesium serum concentrations and coronary slow flow phenomenon.

Mostafa Dastani, Mitra Mokhtari, Ramin Khameneh Bagheri, Pirooz Hassanzadeh, Mahdi Jannati Yazdan Abad, Amir Hooshang Mohammadpour, Sepideh Elyasi

Abstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mostafa Dastani. dastanim@mums.ac.ir.
Mitra Mokhtari. sepidehee@yahoo.com.
Ramin Khameneh Bagheri. khamenehbr@mums.ac.ir.
Pirooz Hassanzadeh. alamatian@yahoo.com.
Mahdi Jannati Yazdan Abad. jannatim971@mums.ac.ir.
Amir Hooshang Mohammadpour. mohamadpoorah@mums.ac.ir.
Sepideh Elyasi. elyasis@mums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pathophysiology of slow flow includes microvascular disorders, endothelial dysfunction, subclinical atherosclerosis, inflammation and anatomical factors. The role of magnesium and zinc in the development of microvascular and endothelial dysfunctions as well as atherosclerosis has been proven in previous studies, and the mechanism of the development has been studied. The aim of current study was to evaluate the serum concentration of zinc and magnesium in patients with epicardial coronary artery slow flow.

design125 patients who referred to Ghaem Hospital in Mashhad were selected based on inclusion and exclusion criteria. Magnesium and Zinc levels were evaluated in patients. The plasma levels of studied elements were compared among the different groups and the rate of coronary artery slow flow was evaluated based on the TIMI score.

resultsThe results of present study indicated that the serum level of Magnesium in the studied groups did not show a significant correlation with rate of coronary artery slow flow (P> 0.05). Serum Zinc concentration was significantly different in the studied groups, which means serum Zinc level in patients without coronary artery occlusion and  without epicardial slow flow were significantly higher than other groups (P> 0.01).

conclusionIn the present study, no significant relationship was found between the serum level of zinc and magnesium with the intensity of coronary artery slow flow based on TIMI, and further studies seem to be needed to investigate this relationship.

Indexed as

MagnesiumNo-Reflow PhenomenonCase-Control StudiesCoronary AngiographyCoronary CirculationCoronary VesselsHumansPilot ProjectsZincMagnesiumZinc

Identifiers

PMID34487108
PMCPMC8477114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.