Evidence map›Paper›PMID 34487074›Full record

SynthesisActa bio-medica : Atenei Parmensis2021

Oncologic outcome of salvage high-intensity focused ultrasound (HIFU) in radiorecurrent prostate cancer. A systematic review.

Umberto Maestroni, Alessandro Tafuri, Francesco Dinale, Davide Campobasso, Alessandro Antonelli, Francesco Ziglioli

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Histotripsy: A Method for Mechanical Tissue Ablation with Ultrasound.Annual review of biomedical engineering · 2024
    Review
  3. Review
  4. Reirradiation salvage radiotherapy for recurrent prostate cancer after primary low-dose brachytherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Umberto MaestroniDepartment of Urology, University-Hospital of Parma. umaestroni@ao.pr.it.
Alessandro TafuriDepartment of Urology, University of Verona. aletaf@hotmail.it.
Francesco DinaleDepartment of Urology, University-Hospital of Parma. dinale@ao.pr.it.
Davide CampobassoDepartment of Urology, University-Hospital of Parma. dcampobasso@ao.pr.it.
Alessandro AntonelliDepartment of Urology, University of Verona. alessandro_antonelli@me.com.
Francesco ZiglioliUniversity-Hospital of Parma, Italy. ziglioli@hotmail.it.
University of Parma · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExternal Beam Radiation Therapy (EBRT) is one of the option available for the treatment of clinically localized prostate cancer. In patients with radiorecurrent localized prostate cancer, Androgen Deprivation Therapy (ADT) is one of the most common therapeutic strategies. However, in the last decades, other salvage treatment options have been investigated, such as brachytherapy, cryoablation and High Intensity Focused Ultrasound (Hifu). MATERIAL AND

methodsThe oncologic outcome of Hifu in a salvage setting after EBRT failure was investigated. We reviewed the literature from 2005 to 2020 in order to report the oncologic outcome of the technique.

resultsA total of 1241 patients were analyzed, with a mean age of 68.6 years and a PSA value of 5.87 ng/mL before treatment. Mean follow-up was 24.3 months after treatment, ranging from 3 to 168 months.

conclusionOur review of the literature revealed that salvage Hifu is effective in the treatment of radiorecurrent clinically localized prostate cancer, with an overall survival of 85.2% at 5 years.

Indexed as

Prostatic NeoplasmsUltrasound, High-Intensity Focused, TransrectalAgedAndrogen AntagonistsHumansMaleNeoplasm Recurrence, LocalProstate-Specific AntigenSalvage TherapyTreatment OutcomeAndrogen AntagonistsProstate-Specific Antigen

Identifiers

PMID34487074
PMCPMC8477121
OpenAlexW3198437951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.