Evidence map›Paper›PMID 34487073›Full record

ArticleActa bio-medica : Atenei Parmensis2021

Phlegmasia cerulea dolens superimposed on disseminated intravascular coagulation in COVID-19.

Daniele Orso, Lisa Mattuzzi, Sara Scapol, Silvia Delrio, Luigi Vetrugno, Tiziana Bove

Open access · greenAbstract readCase Reports
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Daniele OrsoUniversity of Udine. sd7782.do@gmail.com.
Lisa MattuzziUniversity of Udine. mattuzzi.lisa@gmail.com.
Sara ScapolUniversity of Udine. sarascapol@gmail.com.
Silvia DelrioUniversity of Udine. silviadelriomd@gmail.com.
Luigi VetrugnoUniversity of Udine. luigi.vetrugno@uniud.it.
Tiziana BoveUniversity of Udine. tiziana.bove@uniud.it.
University of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 infection has several cardiovascular implications, and coagulopathy is a common abnormality in these patients, often coupled with elevated plasma fibrinogen and D-dimer levels, contributing to adverse outcomes. Phlegmasia cerulea dolens (PCD) is a rare manifestation of deep vein thrombosis. It is life-threatening and can rapidly lead to venous gangrene of the extremity. Only a few cases of COVID-19 associated with PCD are reported in the literature, despite thromboembolism being the common paradigm between the two diseases. We present the case of a 64-year-old adult with acute severe COVID-19 pneumonia who developed PCD despite constantly elevated activated partial thromboplastin time and international normalized ratio.

Indexed as

COVID-19Disseminated Intravascular CoagulationThrombophlebitisVenous ThrombosisAdultGangreneHumansMiddle AgedSARS-CoV-2

Identifiers

PMID34487073
PMCPMC8477088
OpenAlexW3198254429

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.