ReviewActa bio-medica : Atenei Parmensis2021
Diagnosis of acute appendicitis based on clinical scores: is it a myth or reality?
Review in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Diagnostic Accuracy of Non-Contrast CT for Acute Appendicitis in the Emergency Department: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Comparison of RIPASA and ALVARADO scores for risk assessment of acute appendicitis: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Representation and Utilization of Laboratory Data in CT-Based Acute Abdominal Emergency Radiology: A Methodological Content Analysis.Tomography (Ann Arbor, Mich.) · 2026Review
- Article
- Acute appendicitis and its treatment: a historical overview.International journal of colorectal disease · 2025Article
- Magnetic resonance imaging for acute appendicitis in pregnancy: can clinical scores predict when imaging is needed?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Clinical Scoring Systems to Diagnose Complicated Acute Appendicitis in a Rural Hospital: Are They Good Enough?Cureus · 2024Article
- Diagnostic Accuracy of Ileocolic Artery and Vein Diameter for Acute Appendicitis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Complication analysis in acute appendicitis, results from an international multicenter study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Observational
- Evaluating the Diagnostic Accuracy of the Alvarado Score and Abdominal Ultrasound for Acute Appendicitis: A Retrospective Single-Center Study.Open access emergency medicine : OAEM · 2024Article
- Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis.Surgery open science · 2023Article
- Performance and diagnostic accuracy of scoring systems in adult patients with suspected appendicitis.Langenbeck's archives of surgery · 2023Article
- Is it possible to predict the severity of acute appendicitis? Reliability of predictive models based on easily available blood variables.World journal of emergency surgery : WJES · 2023Article
- Gastrointestinal Ultrasound in Emergency Setting.Journal of clinical medicine · 2023Review
- The role of IL-6, thiol-disulfide homeostasis, and inflammatory biomarkers in the prediction of acute appendicitis in children: a controlled study.Pediatric surgery international · 2023Article
- The diagnostic value of the computed tomography scan and ultrasonography in acute appendicitis.American journal of nuclear medicine and molecular imaging · 2023Article
- Diagnosis of Acute Appendicitis: A Cross-sectional Study on Alvarado's Score from a Low Income Country.Open access emergency medicine : OAEM · 2023Article
- Impacts of short-term air pollution exposure on appendicitis admissions: Evidence from one of the most polluted cities in mainland China.Frontiers in public health · 2023Article
- Comparison of scoring systems regarding the gender as a parameter with the traditional scoring systems for predicting appendicitis.Updates in surgery · 2022Article
- Presurgical time and associated factors as predictors of acute perforated appendicitis: a prospective cohort study in a teaching pediatric hospital in Colombia.BMC pediatrics · 2022Article
Corrections and comments
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Authors and funding
12 authors at 12 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim of the work In April 2020, the World Society of Emergency Surgery (WSES) published the first update to the Jerusalem Guidelines on the diagnosis and treatment of acute appendicitis. In this review we have reported a summary of the contemporary evidence from the literature that led to the guidelines statements on the diagnostic strategies for appendicitis. Methods A systematic literature search was performed for studies published on the use of the most common clinical scores and imaging for the diagnosis of appendicitis. Results Alvarado, AIR and AAS scores are sufficiently sensitive (up to 99%) to exclude appendicitis, accurately identifying low-risk patients and decreasing the need for imaging and the negative appendectomy rates in such patients. Conversely, for young patients deemed to be at high-risk of appendicitis according to the scores, because of the high prevalence of the disease in this group of patients (~90%), a negative imaging scan cannot rule out appendicitis. The sensitivity and specificity of CT is reported at 0.91-0.94 and 0.90-0.95. The corresponding results for US are 0.78-0.88 and 0.81-0.94, respectively. Conclusions In young patients, a high-probability score for appendicitis may be used to select patients in which imaging is not needed. When the surgeon deems diagnostic imaging is still needed to confirm appendicitis despite the patient has been scored at high-risk, a conditional CT scan strategy is advised, with CT scan performed only after a negative or equivocal ultrasound scan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.