Evidence map›Paper›PMID 34486659›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2022

Prevalence of Instrumental Activities of Daily Living Difficulties and Associated Cognitive Predictors Across Racial/Ethnic Groups: Findings From the KHANDLE Study.

Michelle L Chan, Chloe W Eng, Paola Gilsanz, Rachel A Whitmer, Dan Mungas, Oanh Meyer, Sarah Tomaszewski Farias

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michelle L ChanDepartment of Neurology, University of California, Davis, California, USA.
Chloe W EngDepartment of Epidemiology and Translational Science, University of California, San Francisco, California, USA.
Paola GilsanzKaiser Permanente Division of Research, Oakland, California, USA.ORCID 0000-0002-7635-381X
Rachel A WhitmerDepartment of Public Health Sciences, University of California, Davis, California, USA.
Dan MungasDepartment of Neurology, University of California, Davis, California, USA.
Oanh MeyerDepartment of Neurology, University of California, Davis, California, USA.
Sarah Tomaszewski FariasDepartment of Neurology, University of California, Davis, California, USA.

Funding

UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVID K JOHNSON · 2021 to 2026
$25.2M
Lifecourse health, cerebral pathology and ethnic disparities in dementia (KHANDLE Study)R01AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GILSANZ, PAOLA, GLYMOUR, MEDELLENA MARIA · 2021 to 2025
$18.0M
Lifecourse health, cerebral pathology and ethnic disparities in dementiaRF1AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GLYMOUR, MEDELLENA MARIA · 2016 to 2016
$13.1M
UC Davis Clinical and Translational Science CenterUL1TR000002 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2012 to 2015
$12.2M
A Culturally-Relevant Approach to Reducing Dementia Caregiver Stress in an Underserved PopulationK01AG052646 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEYER, OANH L · 2016 to 2019
$515k
Alzheimer's Association AARGD-19-619832NCATS NIH HHS UL1 TR000002NIA NIH HHS K01 AG052646NIA NIH HHS P30 AG072972NIA NIH HHS R01 AG052132NIA NIH HHS RF1AG052132
6 · The paper itself

Abstract

objectiveCognitive functioning is associated with instrumental activity of daily living (IADL) performance among older adults. The present study examines potential differences in the prevalence of IADL difficulty and association with cognition across diverse groups.

methodParticipants included 455 non-Hispanic Whites, 395 Blacks, 370 Asians, and 296 Latinos aged 65 years and older without a current dementia diagnosis from the Kaiser Healthy Aging and Diverse Life Experience cohort. Participants' self-reported IADL functioning and cognition was measured across episodic memory and executive functioning.

resultsOlder age, male gender, and being Black were associated with more IADL difficulties. Executive functioning showed a stronger association with IADLs than memory, and it was independent of health status, whereas memory was not. In joint models including both cognitive domains, executive functioning remained a significant predictor of IADL difficulty, but memory did not. Results for both cognitive domains were attenuated with self-rated health added to the joint model. These relationships did not significantly differ across racial/ethnic groups.

conclusionsOur study supports previous work suggesting that Black older adults are at increased risk for IADL disability. This is the first study we are aware of that examined the association between specific cognitive domains and IADL performance across multiple racial/ethnic groups. Findings indicate that cognitive functioning has similar associations with self-reported IADL disability across diverse groups, and that executive functioning plays a particularly important role in IADL disability among older adults without dementia; however, health status largely attenuates the relationship between IADL difficulty and cognition.

Indexed as

Activities of Daily LivingDementiaAgedCognitionEthnicityHumansMaleNeuropsychological TestsPrevalenceExecutive functionFunctional abilitiesMemory

Identifiers

PMID34486659
PMCPMC9071392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.