Evidence map›Paper›PMID 34486432›Full record

Trial reportThe Journal of international medical research2021

Effects of a blood flow restriction exercise under different pressures on testosterone, growth hormone, and insulin-like growth factor levels.

Li Yinghao, Yang Jing, Wang Yongqi, Zhou Jianming, Gao Zeng, Tang Yiting, Li Shuoqi

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Li YinghaoDepartment of Physical Education, Zhengzhou Shengda University, Zhengzhou, China.
Yang JingInternal Medicine-Cardiovascular Department, Tangshan Hongci Hospital, Tangshan, China.
Wang YongqiDepartment of Life Sciences, Inner Mongolia University, Inner Mongolia, China.
Zhou JianmingSchool of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Gao ZengSchool of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Tang YitingSchool of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Li ShuoqiSchool of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.ORCID https://orcid.org/0000-0002-3678-9643
Universiti Sains Malaysia · MYInner Mongolia University · CNTangshan People's Hospital · CNZhengZhou Shengda University Of Economics, Business & Management · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the changes in serum growth hormone (GH), testosterone, and insulin-like growth factor 1 (IGF-1) during low-intensity resistance exercise under different cuff pressures.

methodsWe performed a single-blind, cross-over design study. Twenty-five healthy young men performed three exercise protocols as follows: 1) no blood flow restriction exercise (control group), 2) resistance exercise at 40% of arterial occlusion pressure (AOP) (low group), and 3) resistance exercise at 70% of AOP (high group). Blood lactate, GH, testosterone, and IGF-1 levels were measured at four time points.

resultsThere were no differences in the indices before exercise. The blood flow restriction exercise under different pressures had different effects on each index and there was an interactive effect. GH levels were significantly higher in the high group than in the other groups after exercise. Immediately after exercise, IGF-1 and testosterone levels were significantly higher in the high group than in the other groups. At 15 minutes after exercise, testosterone levels were significantly higher in the high group than in the other groups.

conclusionsLow-intensity resistance exercise combined with blood flow restriction effectively increases GH, IGF-1, and testosterone levels in young men. Increasing the cuff pressure results in greater levels of hormone secretion.

Indexed as

Growth HormoneHuman Growth HormoneExerciseHumansInsulin-Like Growth Factor IMaleSingle-Blind MethodTestosteroneGrowth HormoneHuman Growth HormoneInsulin-Like Growth Factor ITestosteroneBlood flow restrictioncuff pressureinsulin-like growth factor 1myogenic hormoneresistance exercisetestosterone

Identifiers

PMID34486432
PMCPMC8424606
OpenAlexW3198340297

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.