Evidence map›Paper›PMID 34486179›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

A Water Soluble Pd

Xander Schaapkens, Roy N van Sluis, Eduard O Bobylev, Joost N H Reek, Tiddo J Mooibroek

Open access · bronzeAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Carbohydrate-Binding Mechanism and Therapeutic Potential of Lectin Mimics.Advances in experimental medicine and biology · 2026
    Review
  2. A Synthetic Lectin for Glucuronate.ACS central science · 2025
    Article
  3. Molecular Tweezers for Biomimetic Recognition of Carbohydrates.Chembiochem : a European journal of chemical biology · 2025
    Review
  4. Review
  5. LiBFAngewandte Chemie (International ed. in English) · 2022
    Article
  6. A Water Soluble PdChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xander SchaapkensVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam (The, Netherlands.
Roy N van SluisVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam (The, Netherlands.
Eduard O BobylevVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0002-1563-0190
Joost N H ReekVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0001-5024-508X
Tiddo J MooibroekVan 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0002-9086-1343
Institute for Atomic and Molecular Physics · NL

Funding

stichting voor de technische wetenschappen 723.015.006
6 · The paper itself

Abstract

The sialic acid N-acetylneuraminic acid (Neu5Ac) and its derivatives are involved in many biological processes including cell-cell recognition and infection by influenza. Molecules that can recognize Neu5Ac might thus be exploited to intervene in or monitor such events. A key obstacle in this development is the sparse availability of easily prepared molecules that bind to this carbohydrate in its natural solvent; water. Here, we report that the carbohydrate binding pocket of an organic soluble [Pd

Indexed as

MonosaccharidesWaterGuanidineHydrogen BondingSolventsGuanidineMonosaccharidesSolventsWatercarbohydrate recognitionhost-guest systemsmolecular recognitionself-assemblysialic acids

Identifiers

PMID34486179
PMCPMC8518546
OpenAlexW3196728639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.