Evidence map›Paper›PMID 34486092›Full record

ArticleInternational journal of implant dentistry2021

Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study.

Goli Khaleghi, Hoda Mahdavi, Seied Rabi Mahdavi, Benyamin Khajetash, Alireza Nikoofar, Mohammad Hosntalab, Mahdi Sadeghi, Reza Reiazi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of implant dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Planning issues on linac-based stereotactic radiotherapy.World journal of clinical cases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Goli KhaleghiMedical Radiation Engineering Department, Science and Research Branch, Islamic Azad University, Daneshgah Blvd., Simon Bolivar Blvd., P.O. Box: 14515-775, Tehran, Iran.
Hoda MahdaviRadiation Biology Research Center, Iran University of Medical Sciences, Shahid Hemmat Highway, P.O. Box: 14665-354, Tehran, Iran. Mahdavi.h@iums.ac.ir.ORCID 0000-0002-8433-6331
Seied Rabi MahdaviRadiation Biology Research Center, Iran University of Medical Sciences, Shahid Hemmat Highway, P.O. Box: 14665-354, Tehran, Iran.
Benyamin KhajetashMedical Physics Department, School of Medicine, Iran University of Medical Sciences, Shahid Hemmat Highway, P.O. Box: 14155-6183, Tehran, Iran.
Alireza NikoofarRadiation Oncology Department, Iran University of Medical Sciences, Firoozgar hospital, Beh-Afarin St., Karimkhane-Zand Blvd., P.O. Box: 1593747811, Tehran, Iran.
Mohammad HosntalabMedical Radiation Engineering Department, Science and Research Branch, Islamic Azad University, Daneshgah Blvd., Simon Bolivar Blvd., P.O. Box: 14515-775, Tehran, Iran.
Mahdi SadeghiMedical Physics Department, School of Medicine, Iran University of Medical Sciences, Shahid Hemmat Highway, P.O. Box: 14155-6183, Tehran, Iran.
Reza ReiaziPrincess Margaret Cancer Center, University Health Network, 101 College Street, P.O. Box: M5G 1L7, Ontario, Toronto, Canada.
Iran University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaterials with high atomic numbers are part of the composition of dental implant systems. In radiotherapy of oral cavity cancers, an implant can cause dose perturbations that affect target definition, dose calculation, and dose distribution. In consequence, this may result in poor tumor control and higher complications. In this study, we evaluated dose homogeneity when a dental implant replaced a normal tooth. We also aimed to evaluate the concordance of dose calculations with dose measurements. MATERIALS AND

methodsIn this study, 2 sets of planning CT scans of a phantom with a normal tooth and the same phantom with the tooth replaced by a Z1 TBR dental implant system were used. The implant system was composed of a porcelain-fused-to-metal crown and titanium with a zirconium collar. Three radiotherapy plans were designed when the density of the implant material was corrected to match their elements, or when all were set to the density of water, or when using the default density conversion. Gafchromic EBT-3 films at the level of isocenter and crowns were used for measurements.

resultsAt the level of crowns, upstream and downstream dose calculations were reduced when metal kernels were applied (M-plan). Moreover, relatively measured dose distribution patterns were most similar to M-plan. At this level, relative to the non-implanted phantom, mean doses values were higher with the implant (215.93 vs. 192.25), also, new high-dose areas appeared around a low-dose streak forward to the implant (119% vs. 95%).

conclusionsImplants can cause a high dose to the oral cavity in radiotherapy because of extra scattered radiation. Knowledge of the implant dimensions and defining their material enhances the accuracy of calculations.

Indexed as

Dental ImplantsMouth NeoplasmsHumansPhantoms, ImagingRadiotherapy DosageRadiotherapy Planning, Computer-AssistedDental ImplantsDensity correctionDental implantFilm dosimetryPhantom

Identifiers

PMID34486092
PMCPMC8419140
OpenAlexW3198135792

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.