Evidence map›Paper›PMID 34486071›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Two experts and a newbie: [

Sophie Stotz, Johannes Kinzler, Anne T Nies, Matthias Schwab, Andreas Maurer

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Rapid cleavage of 6-[EJNMMI radiopharmacy and chemistry · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. [Journal of clinical medicine · 2024
    Review
  9. PET imaging of PARP expression usingEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  10. [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  11. Review
  12. Fully Automated, High-Dose Radiosynthesis of [Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sophie StotzWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Roentgenweg 15, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-4020-1088
Johannes KinzlerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Roentgenweg 15, 72076, Tuebingen, Germany.
Anne T NiesCluster of Excellence iFIT (EXC 2180) "Image Guided and Functionally Instructed Tumor Therapies", Eberhard Karls University Tuebingen, Tuebingen, Germany.ORCID http://orcid.org/0000-0001-6862-0730
Matthias SchwabCluster of Excellence iFIT (EXC 2180) "Image Guided and Functionally Instructed Tumor Therapies", Eberhard Karls University Tuebingen, Tuebingen, Germany.
Andreas MaurerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Roentgenweg 15, 72076, Tuebingen, Germany. andreas.maurer@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0003-2412-5361
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology · DESiemens (Germany) · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImaging of PARP expression has emerged as valuable strategy for prediction of tumor malignancy. While [

methodsWe developed a less lipophilic variant of [

resultsTogether with decent uptake of all three radiotracers in the xenografts (tumor-to-blood ratios 3.41 ± 0.83, 3.99 ± 0.99, and 2.46 ± 0.35, respectively, for [

conclusionThese findings imply that [

Indexed as

Liver NeoplasmsPoly(ADP-ribose) Polymerase InhibitorsAnimalsCell Line, TumorHumansMiceMice, Inbred NODMice, SCIDPositron-Emission TomographyPoly(ADP-ribose) Polymerase InhibitorsOncologyPARPPARP inhibitorsPET imagingRadiotracers

Identifiers

PMID34486071
PMCPMC8803746
OpenAlexW3198285319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.