Evidence map›Paper›PMID 34485783›Full record

ArticleCurrent opinion in physiology2020

Recent advances in modeling sleep: from the clinic to society and disease.

John H Abel, Kimaya Lecamwasam, Melissa A St Hilaire, Elizabeth B Klerman

Abstract read
In one paragraph

Article in Current opinion in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John H AbelDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114.
Kimaya LecamwasamDepartment of Neuroscience, Wellesley College, Wellesley, MA 02481.
Melissa A St HilaireDivision of Sleep Medicine, Harvard Medical School, Boston, MA 02115.
Elizabeth B KlermanDivision of Sleep Medicine, Harvard Medical School, Boston, MA 02115.

Funding

TRANSPLANTATION ANALYSIS OF CIRCADIAN RHYTHMS AND AGINGP01AG009975 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 1991 to 2018
$23.1M
TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Influence of sleep regularity on circadian rhythms, learning, performance, and moodR01HL128538 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2016 to 2019
$3.6M
Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in WomenR01AG053838 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI JOFFE, HADINE · 2017 to 2020
$3.5M
Circadian Lipidomics in Constant Routine, Forced Desynchrony, and Non-lab SettingR01HL132556 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KRISTAL, BRUCE S · 2016 to 2019
$3.5M
Lipidomics Biomarkers Link Sleep Restriction to Adiposity Phenotype, Diabetes, and Cardiovascular RiskR01HL140335 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KRISTAL, BRUCE S · 2018 to 2021
$3.4M
Sleep duration required to restore performance during chronic sleep restrictionR01HL114088 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2012 to 2015
$3.1M
Bright light modulation of non-motor symptoms in Parkinson's diseaseR01NS099055 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI VIDENOVIC, ALEKSANDAR · 2017 to 2021
$3.0M
Multi-scale modeling of sleep behaviors in social networksR01GM105018 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A, KLERMAN, ELIZABETH B. · 2013 to 2017
$2.4M
Sleep Duration Required to Restore Performance during Chronic Sleep RestrictionK24HL105664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2010 to 2019
$1.8M
Circadian Rhythms Regulation in Pre-Manifest SynucleinopathiesR21NS108022 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI VIDENOVIC, ALEKSANDAR · 2018 to 2019
$463k
Automatic Control of Propanidid and Propofol Anesthesia-Induced UnconsciousnessF32AG064886 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI ABEL, JOHN HANS · 2019 to 2020
$132k
NHLBI NIH HHS K24 HL105664NHLBI NIH HHS R01 HL114088NHLBI NIH HHS R01 HL128538NHLBI NIH HHS R01 HL132556NHLBI NIH HHS R01 HL140335NHLBI NIH HHS T32 HL007901NIA NIH HHS F32 AG064886NIA NIH HHS P01 AG009975NIA NIH HHS R01 AG053838NIGMS NIH HHS R01 GM105018NINDS NIH HHS R01 NS099055NINDS NIH HHS R21 NS108022
6 · The paper itself

Abstract

In the past few decades, advances in understanding sleep-wake neurophysiology have occurred hand-in-hand with advances in mathematical modeling of sleep and wake. In this review, we summarize recent updates in modeling the timing and durations of sleep and wake, the underlying neurophysiology of sleep and wake, and the application of these models in understanding cognition and disease. Throughout, we highlight the role modeling has played in developing our understanding of sleep and its underlying mechanisms. We present open questions and controversies in the field and propose the utility of individualized models of sleep for precision sleep medicine.

Indexed as

circadian rhythmcognitionmathematical modelingprecision medicinesleep

Identifiers

PMID34485783
PMCPMC8415470

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.