ArticleNeurobiology of pain (Cambridge, Mass.)
Pain after upper limb surgery under peripheral nerve block is associated with gut microbiome composition and diversity.
Article in Neurobiology of pain (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Interactions Between Perioperative Anesthesia Management and Gut Microbiota: Current Research Advances.Cellular and molecular neurobiology · 2026Review
- The gut microbiota in persistent post-operative pain following breast cancer surgery.Scientific reports · 2024Observational
- Review
- Probiotics in Postoperative Pain Management.Journal of personalized medicine · 2023Review
- Gut Microbiome in Anesthesiology and Pain Medicine.Anesthesiology · 2022Review
- Chronic pain and complex regional pain syndrome are associated with alterations to the intestinal microbiota in both humans and mice. An observational cross-sectional study.Neurobiology of pain (Cambridge, Mass.)Article
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Authors and funding
10 authors.
Funding
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Abstract
Gut microbiota play a role in certain pain states. Hence, these microbiota also influence somatic pain. We aimed to determine if there was an association between gut microbiota (composition and diversity) and postoperative pain. Patients (n = 20) undergoing surgical fixation of distal radius fracture under axillary brachial plexus block were studied. Gut microbiota diversity and abundance were analysed for association with: (i) a verbal pain rating scale of < 4/10 throughout the first 24 h after surgery (ii) a level of pain deemed "acceptable" by the patient during the first 24 h following surgery (iii) a maximum self-reported pain score during the first 24 h postoperatively and (iv) analgesic consumption during the first postoperative week. Analgesic consumption was inversely correlated with the Shannon index of alpha diversity. There were also significant differences, at the genus level (including
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