Evidence map›Paper›PMID 34485759›Full record

ArticleAmerican journal of ophthalmology case reports2021

Unilateral retinopathy post perilesional interferon α2b injections for ocular surface squamous cell carcinoma.

Shiv Dalla, Mary Champion, Radwan Ajlan, John E Sutphin, Jason A Sokol

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Topical interferon therapy in uveitic macular edema.Indian journal of ophthalmology · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shiv DallaUniversity of Kansas School of Medicine, Kansas City, KS, USA.
Mary ChampionUniversity of Kansas Medical Center, Department of Ophthalmology, Kansas City, KS, USA.
Radwan AjlanUniversity of Kansas Medical Center, Department of Ophthalmology, Kansas City, KS, USA.
John E SutphinUniversity of Kansas Medical Center, Department of Ophthalmology, Kansas City, KS, USA.
Jason A SokolUniversity of Kansas Medical Center, Department of Ophthalmology, Kansas City, KS, USA.
University of Kansas Medical Center · USUniversity of Kansas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the clinical course of a patient presenting with unilateral retinopathy after perilesional interferon alpha injections for treatment of ocular surface squamous cell carcinoma. OBSERVATIONS: A patient, who was being treated with interferon alpha for ocular squamous cell carcinoma, presented with new onset decreased vision in her left eye. Upon examination, she was found to have cotton wool spots and retinal hemorrhages in the affected eye. CONCLUSIONS AND IMPORTANCE: Retinopathy is a well-documented side effect of systemic usage of interferon alpha. However, retinopathy has not been well discussed in the scenario of perilesional injections of interferon. It is important for clinicians to monitor for such pathology when using interferon alpha not only systemically, but also locally.

Indexed as

Interferon α2bOcular squamous neoplasiaRetinopathy

Identifiers

PMID34485759
PMCPMC8405888
OpenAlexW3196678093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.