Evidence map›Paper›PMID 34485716›Full record

ArticleBiochemistry and biophysics reports2021

The high expression of miR-31 in lung adenocarcinoma inhibits the malignancy of lung adenocarcinoma tumor stem cells.

Ran Xu, Tianhua Liu, Ling Zuo, Dongqing Guo, Guancheng Ye, Jingjing Jiang, Xue Yu, Shujing Zhang, Chunying Hou

Open access · goldAbstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ran XuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Tianhua LiuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Ling ZuoSchool of Life Science, Beijing University of Chinese Medicine, Beijing, China.
Dongqing GuoSchool of Life Science, Beijing University of Chinese Medicine, Beijing, China.
Guancheng YeSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Jingjing JiangSchool of the Humanities, Beijing University of Chinese Medicine, Beijing, China.
Xue YuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Shujing ZhangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Chunying HouSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapies for lung adenocarcinoma (LUAD) are mainly limited by drug resistance, metastasis or recurrence related to cancer stem cells (CSCs) with high proliferation and self-renewing. This research validated that miR-31 was over-expressed in LUAD by the analysis of generous clinical samples data. And the results of clinical data analysis showed that high expression of miR-31 was more common in patients with worse prognosis. The genes differentially expressed in LUAD tissues compared with normal tissues and A549CD133

Indexed as

CSCsLUADMetastasisMiR-31Tumorigenesis

Identifiers

PMID34485716
PMCPMC8408630
OpenAlexW3196790213

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.