Evidence map›Paper›PMID 34485530›Full record

ArticleBioMed research international2021

Morroniside Promotes PGC-1

Junwei Gao, Peng Liu, Zhengri Shen, Ke Xu, Chenguang Wu, Feng Tian, Ming Chen, Lifan Wang, Ping Li

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Cornelian Cherry (International journal of molecular sciences · 2024
    Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Junwei GaoInstitute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 101300, China.ORCID https://orcid.org/0000-0003-4001-6026
Peng LiuShunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing 101300, China.ORCID https://orcid.org/0000-0003-0862-2800
Zhengri ShenShunyi Hospital, Beijing Traditional Chinese Medicine Hospital, Beijing 101300, China.
Ke XuRenal Division, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.
Chenguang WuRenal Division, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.
Feng TianRenal Division, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.
Ming ChenRenal Division, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.
Lifan WangRenal Division, Heilongjiang Academy of Chinese Medicine Sciences, Harbin 150036, China.ORCID https://orcid.org/0000-0002-1806-3152
Ping LiBeijing Key Lab Immune-Mediated Inflammatory Diseases, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.ORCID https://orcid.org/0000-0002-3315-2276
Heilongjiang Academy of Sciences · CNShunyi Hospital of Beijing Traditional Chinese Medicine Hospital · CNChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid deposition is an etiology of renal damage caused by lipid metabolism disorder in diabetic nephropathy (DN). Thus, reducing lipid deposition is a feasible strategy for the treatment of DN. Morroniside (MOR), an iridoid glycoside isolated from the Chinese herb

Indexed as

AnimalsCell LineEnzyme InhibitorsEpithelial CellsGlucoseGlycosidesKidney DiseasesKidney TubulesLipid Metabolism DisordersMicePalmitic AcidPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant ExtractsSignal TransductionSweetening AgentsEnzyme InhibitorsGlucoseGlycosidesmorronisidePalmitic AcidPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPlant ExtractsPpargc1a protein, mouseSweetening Agents

Identifiers

PMID34485530
PMCPMC8410408
OpenAlexW3194661979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.