ArticleSouthern African journal of infectious diseases2019
The accuracy of extended-spectrum beta-lactamase detection in
Article in Southern African journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Antibacterial potential, DNA binding and molecular docking investigations of newly green synthesized zinc oxide/chitosan/vancomycin nanocomposite using Bacillus licheniformis ATCC 4527 against some drug-resistant bacteria.Microbial cell factories · 2026Article
- Prevalence of multi-drug resistant and extended-spectrum β-lactamase producing Escherichia coli and Klebsiella pneumoniae among meat products sold at Sohag Governorate, Egypt.BMC microbiology · 2025Article
- Efficient Absorbance-Based Assay for Rapid Antibiotic Susceptibility Testing of Enterobacterales.Antibiotics (Basel, Switzerland) · 2024Article
- ROCker Models for Reliable Detection and Typing of Short-Read Sequences Carrying β-Lactamase Genes.mSystems · 2022Article
- Susceptibility of CommensalAntibiotics (Basel, Switzerland) · 2021Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhenotypic detection of extended-spectrum beta-lactamases (ESBLs) is based on the inhibition of ESBL enzymes by β-lactamase inhibitors and on the comparison of cephalosporin activity with or without a β-lactamase inhibitor. Many South African diagnostic laboratories rely on the Vitek 2 for automated susceptibility testing and for ESBL detection. However, the Gram-negative susceptibility card currently used locally (AST-N255) has been modified and its accuracy for ESBL detection is not known.
methodsWe randomly selected 50 isolates of
resultsThe sensitivity of Vitek 2 system for detection of ESBLs was 33/36 or 92% (78% - 97%) for
conclusionUsing a composite reference standard of the phenotypic and genotypic methods employed in this study, no Vitek-categorised ESBL
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Registered trials
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