Evidence map›Paper›PMID 34485178›Full record

ArticleFrontiers in cellular and infection microbiology2021

Development of an Antibiotic Resistance Breaker to Resensitize Drug-Resistant

Gopalakrishnan Thamilselvan, Hema Bhagavathi Sarveswari, Sahana Vasudevan, Alex Stanley, Karthi Shanmugam, Pothiappan Vairaprakash, Adline Princy Solomon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Structural characteristics, functions, and counteracting strategies of biofilms inComputational and structural biotechnology journal · 2025
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gopalakrishnan ThamilselvanQuorum Sensing Laboratory, Centre of Research in Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Hema Bhagavathi SarveswariQuorum Sensing Laboratory, Centre of Research in Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Sahana VasudevanQuorum Sensing Laboratory, Centre of Research in Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Alex StanleyDepartment of Bioinformatics, School of Chemical & Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Karthi ShanmugamQuorum Sensing Laboratory, Centre of Research in Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Pothiappan VairaprakashDepartment of Chemistry, School of Chemical & Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
Adline Princy SolomonQuorum Sensing Laboratory, Centre of Research in Infectious Diseases, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, India.
SASTRA University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efflux pumps are one of the predominant microbial resistant mechanisms leading to the development of multidrug resistance. In

Indexed as

Methicillin-Resistant Staphylococcus aureusPharmaceutical PreparationsAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsComputer SimulationDrug Resistance, MicrobialMicrobial Sensitivity TestsStaphylococcus aureusAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsPharmaceutical Preparationsantimicrobialsbioisostereboron acidefflux PumpNorAStaphylococcus aureus

Identifiers

PMID34485178
PMCPMC8415528
OpenAlexW3193280694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.