Evidence map›Paper›PMID 34485144›Full record

ArticleFrontiers in oncology2021

The Impact of Smoking, Alcohol Use, Recurrent Disease, and Age on the Development of Neck Fibrosis in Head and Neck Cancer Patients Following Radiation Therapy.

Connor L Pratson, Michael C Larkins, Brandon H Karimian, Caitrin M Curtis, Pamela A Lepera, Brian N Brodish, Andrew W Ju

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Chronic radiation-induced dermatitis: what is new in 2024? A narrative review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Connor L PratsonBrody School of Medicine, East Carolina University, Greenville, NC, United States.
Michael C LarkinsBrody School of Medicine, East Carolina University, Greenville, NC, United States.
Brandon H KarimianBrody School of Medicine, East Carolina University, Greenville, NC, United States.
Caitrin M CurtisBrody School of Medicine, East Carolina University, Greenville, NC, United States.
Pamela A LeperaDivision of Hematology/Oncology, Department of Internal Medicine, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Brian N BrodishEastern Carolina Head and Neck Surgery, Greenville, NC, United States.
Andrew W JuDepartment of Radiation Oncology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
East Carolina University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a paucity of information regarding the demographic factors associated with the development of neck fibrosis in head and neck cancer (HNC) patients following radiotherapy. A retrospective review of all patients being treated for HNC at a tertiary care center between 2013 and 2017 was performed. Chi-squared and Mann-Whitney U tests were used to identify differences in incidence and grade of fibrosis, respectively, between populations. A total of 90 patients aged 19 to 99 years were included. Factors associated with an increased incidence of fibrosis included smoking during radiotherapy (

Indexed as

alcohol and tobacco usefibrosishead and neck cancerradiotherapyrisk factors

Identifiers

PMID34485144
PMCPMC8415001
OpenAlexW3194894878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.