ArticleWorld journal of orthopedics2021
Complications in growth-friendly spinal surgeries for early-onset scoliosis: Literature review.
Article in World journal of orthopedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07429656 (Active Apex Correction), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Active Apex Correction (APC) for Early Onset Scoliosis. Early Results of a Pilot Study.
Who cites it
19 citing papers in PubMed, 20 citations in OpenAlex.
- Evolving surgical strategies in myelomeningocele (MMC): shift toward index fusion with stable complication rates.Spine deformity · 2026Article
- Benefits and complications: A systematic review and meta-analysis of serial casting in early onset scoliosis.Journal of children's orthopaedics · 2026Review
- Shilla growth guidance vs. distraction-based constructs for severe, early-onset congenital scoliosis treated with 3-column osteotomy.Spine deformity · 2026Article
- Age at Initial Surgery and Surgical Burden in Congenital Spinal Deformity.Medicina (Kaunas, Lithuania) · 2026Article
- Growth modulation and dynamic correction of early-onset thoracic scoliosis using a PEEK spring rib plate system: a porcine model study.Spine deformity · 2026Article
- Artificial intelligence in early onset scoliosis: a scoping review.Spine deformity · 2026Article
- Decade-Long Progress of a Patient with Early Onset Scoliosis Treated with Serial Casting, Traditional Growth Rods and Posterior Spinal Instrumentation with Fusion - a Case Report.The archives of bone and joint surgery · 2026Article
- Outcomes of Growth Rod Distraction in Early Onset Scoliosis: A Case Series From a Tertiary Spine Centre.Cureus · 2026Article
- Qualitative Analysis of the Literature on Distraction-Based Techniques for Early-Onset Scoliosis.Cureus · 2025Review
- Risk of proximal junctional kyphosis after revision of growing rod constructs.Spine deformity · 2025Article
- Failure to replace removed growth friendly implants results in deteriorating radiographic outcomes.Spine deformity · 2025Article
- "Cured" patients with early-onset idiopathic scoliosis after serial casting are at risk of recurrence at intermediate follow-up.Spine deformity · 2025Article
- Safety and efficacy of waterproof casting for early onset scoliosis.Spine deformity · 2024Article
- Radiological Outcomes of Magnetically Controlled Growing Rods for the Treatment of Children with Various Etiologies of Early-Onset Scoliosis-A Multicenter Study.Journal of clinical medicine · 2024Article
- Growing Rod versus Posterior Spinal Fusion Treatment of Juvenile Idiopathic Scoliosis: Unique Characteristics and Surgical Outcomes.Healthcare (Basel, Switzerland) · 2024Article
- Instrumentation failure following pediatric spine deformity growth-sparing surgery using traditional growing rods or vertical expandable prosthetic titanium ribs.BMC musculoskeletal disorders · 2024Review
- Metabolic Imbalances and Bone Remodeling Agents in Adolescent Idiopathic Scoliosis: A Study in Postmenarcheal Girls.International journal of molecular sciences · 2023Article
- Implant-Related Complications Do Not Interfere with Corrections with the Shilla Technique in Early Onset Scoliosis: Preliminary Results.Children (Basel, Switzerland) · 2023Article
- Relook into the Risk Factors of Proximal Junctional Kyphosis in Early Onset Scoliosis Patients: Does the Location of Upper Instrumented Vertebra in Relation to the Sagittal Apex Matter?Orthopaedic surgery · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe treatments for early-onset scoliosis (EOS), defined as curvature of the spine with onset before 10 years of age, continue to pose a great challenge for pediatric orthopedics. The treatment goals for EOS include minimizing spinal deformity while maximizing thoracic volume and pulmonary function. Different surgical techniques have different advantages and drawbacks; however, the two major concerns in the management of EOS are repeated surgeries and complications.
aimTo review the current literature to assess the safety of EOS surgical treatment in terms of the rate of complications and unplanned surgeries.
methodsIn January 2021 two independent reviewers systematically searched three electronic medical databases (PubMed, the Cochrane Library, and Embase) for relevant articles. Every step of the review was done according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Due to the heterogeneity of articles and topics after data analysis, a descriptive (synthetic) analysis was performed.
resultsA total of 2136 articles were found. Forty articles were included in this systematic review, after applying our inclusion and exclusion criteria. EOS surgery has a varying but high rate of complications. The most frequent complications were categorized as implant (54%), general (17%), wound (15%) and alignment (12%). The rate of complications might have been even higher than reported, as some authors do not report all types of complications. About 54% of patients required unplanned surgeries due to complications, which comprised 15% of all surgeries.
conclusionThe literature concerning the definitions, collection, and interpretation of data regarding EOS surgery complications is often difficult to interpret. This creates problems in the comparison, analysis, and improvement of spine surgery practice. Additionally, this observation indicates that data on the incidence of complications can be underestimated, and should be interpreted with caution. Awareness of the high rate of complications of EOS surgery is crucial, and an optimal strategy for prevention should become a priority.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.