Evidence map›Paper›PMID 34485102›Full record

ArticleWorld journal of orthopedics2021

Thromboelastography in elective total hip arthroplasty.

Patryck Lloyd-Donald, Wen-Shen Lee, Guo-Ming Liu, Rinaldo Bellomo, Larry McNicol, Laurence Weinberg

Open access · diamondAbstract read
In one paragraph

Article in World journal of orthopedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Patryck Lloyd-DonaldDepartment of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.
Wen-Shen LeeDepartment of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.
Guo-Ming LiuDepartment of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.
Rinaldo BellomoDepartment of Intensive Care, Austin Hospital, Melbourne 3084, Victoria, Australia.
Larry McNicolDepartment of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.
Laurence WeinbergDepartment of Anesthesia, Austin Health, Heidelberg 3084, Victoria, Australia.
Austin Health · AUUniversity of Melbourne · AUAustin Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypercoagulability plays an important role in predisposing patients to venous thromboembolism (VTE) after total hip arthroplasty (THA). We used thromboelastography (TEG) to examine the coagulation status of patients undergoing THA.

aimTo examine coagulation as measured by TEG in patients undergoing THA who received standard VTE chemoprophylaxis with enoxaparin.

methodsAfter ethical approval, we performed a retrospective analysis of data collected in patients undergoing primary elective THA. We analyzed TEG data on samples performed before skin incision, intraoperatively and for 5 d postoperatively. Conventional coagulation tests were performed preoperatively and on postoperative day 5.

resultsTwenty patients undergoing general anesthesia and 32 patients undergoing spinal anesthesia (SA) were included. TEG demonstrated a progressively hypercoagulable state postoperatively, characterized by elevated maximum amplitude. TEG also demonstrated transient intraoperative hypercoagulability in patients receiving SA. In contrast, conventional coagulation tests were normal in all patients, pre- and postoperatively, except for an increase in plasma fibrinogen day 5 postoperatively.

conclusionDespite VTE prophylaxis, patients following total hip replacement remain in a hypercoagulable state as measured by both TEG and conventional tests. This group may benefit from more optimal anticoagulation and/or additional perioperative hemostatic monitoring,

Indexed as

AnesthesiaHip arthroplastyHypercoagulabilityOrthopedicSurgeryThrombelastography

Identifiers

PMID34485102
PMCPMC8384610
OpenAlexW3192673161

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.