Evidence map›Paper›PMID 34485013›Full record

ArticleJIMD reports2021

Sapropterin dihydrochloride therapy in dihydropteridine reductase deficiency: Insight from the first case with molecular diagnosis in Brazil.

Charles Marques Lourenço, Janaina Dovidio, Isabela F Lopes, Laís C Silva, Marcela Almeida, Laura Vagnini, Jacqueline Fonseca, Zumira A Carneiro, Beat Thöny

Open access · goldAbstract readCase Reports
In one paragraph

Article in JIMD reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Charles Marques LourençoCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.ORCID https://orcid.org/0000-0002-2296-6098
Janaina DovidioCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.
Isabela F LopesCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.
Laís C SilvaCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.
Marcela AlmeidaCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.
Laura VagniniCentro Paulista de Diagnóstico e Pesquisa em Genética Clínica São Paulo Brazil.
Jacqueline FonsecaLaboratório DLE Bioquímica Genética Rio de Janeiro Brazil.
Zumira A CarneiroCentro Universitário Estácio de Ribeirão Preto São Paulo Brazil.
Beat ThönyDivision of Metabolism University Children's Hospital Zürich Switzerland.
Centro Paulista de Investigação Clinica · BRUniversity Children's Hospital Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetrahydrobiopterin (BH

Indexed as

BH4 deficiencydihydropteridine reductase (DHPR) genehyperphenylalaninemial‐DOPAtetrahydrobiopterin

Identifiers

PMID34485013
PMCPMC8411105
OpenAlexW3157516879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.