Evidence map›Paper›PMID 34484792›Full record

ArticleSAGE open medical case reports2021

The 13-year bleed: Exuberant amyloid angiopathies, angiodysplasias, and acquired coagulopathies of the gut.

Larnelle N Simms, Laura Suzanne K Suarez, Khaled Deeb, Jose Proenza

Open access · goldAbstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Larnelle N SimmsInternal Medicine Resident, University of Miami Palm Beach Regional GME Consortium, Atlantis, FL, USA.ORCID https://orcid.org/0000-0001-8644-6836
Laura Suzanne K SuarezInternal Medicine Resident, University of Miami Palm Beach Regional GME Consortium, Atlantis, FL, USA.ORCID https://orcid.org/0000-0003-2334-4976
Khaled DeebDepartment of Internal Medicine, West Palm Beach Veterans Affairs Medical Center, West Palm Beach, FL, USA.
Jose ProenzaDepartment of Gastroenterology, West Palm Beach Veterans Affairs Medical Center, West Palm Beach, FL, USA.
University of Miami · USWest Palm Beach VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloidosis is a disorder characterized by extracellular deposits of proteins that are prone to aggregate and form insoluble fibrils. Amyloid deposits limited to a single organ or tissue without the involvement of any other site in the body is uncommon. We report a 75-year-old man with previously treated non-Hodgkin's lymphoma who presented with recurrent gastrointestinal hemorrhage. Histopathology showed amyloid deposition within vascular malformations. His bleeding continued with the cause rooted in the fundamental building blocks-clotting factors. We discuss the interplay of the pathophysiology of lymphoma, amyloidosis, and factor X deficiency in a patient with preexisting angiodysplasias leading to refractory gastrointestinal bleeding. To our knowledge, there are only 3 reported cases of concomitant amyloidosis and angiodysplasia in the colon, and none involving the small bowel.

Indexed as

Amyloidosisangiodysplasiafactor X deficiencyhemorrhage

Identifiers

PMID34484792
PMCPMC8414616
OpenAlexW3197311344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.