Evidence map›Paper›PMID 34484738›Full record

ArticleTherapeutic advances in infectious disease

Status of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara University Teaching Hospital in Southwestern Uganda.

Israel Kiiza Njovu, Benson Musinguzi, James Mwesigye, Kennedy Kassaza, Joseph Turigurwa, Edwin Nuwagira, Joel Bazira, Taseera Kabanda, Moses Mpeirwe, Lucas Ampaire and 4 more

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In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Israel Kiiza NjovuDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Benson MusinguziDepartment of Medical Laboratory Science, Faculty of Health Sciences, Muni University, Arua, Uganda.ORCID https://orcid.org/0000-0002-1211-4617
James MwesigyeDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Kennedy KassazaDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Joseph TurigurwaDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Edwin NuwagiraDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Joel BaziraDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Taseera KabandaDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Moses MpeirweDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Lucas AmpaireDepartment of Medical Laboratory Sciences, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Andrew MutekangaDepartment of Internal Medicine, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
James KiguliDepartment of Microbiology and Immunology, School of Health Sciences, Soroti University, Soroti, Uganda.
Beatrice AchanDepartment of Microbiology, School of Biomedical Sciences, Makerere University, Uganda.
Herbert ItabangiDepartment of Microbiology, Mycology Unit, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Mbarara University of Science and Technology · UGMakerere University · UGSoroti University · UGSt. Augustine International University · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less attention has been paid to them. In this study we determined the prevalence of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara Regional Referral Hospital.

methodThis was a hospital based cross sectional survey. Sputum samples were collected from each study participant. For each sample, the following tests were performed: Sabouraud dextrose agar for fungal culture, GeneXpert for

resultsOut of 113 study participants, 80 (70.7%) had pulmonary fungal pathogens whilst those with pulmonary tuberculosis numbered five (4.4%).

conclusionOur findings highlight the diversity of neglected pulmonary fungal pathogens whose known medical importance in causing pulmonary mycoses cannot be overemphasised. Therefore this presents a need for routine diagnosis for pulmonary mycoses among TB suspects and set-up of antimicrobial profile for pulmonary fungal isolates to support clinical management of these cases.

Indexed as

pulmonary fungal infectionspulmonary fungal pathogenspulmonary mycosespulmonary tuberculosis

Identifiers

PMID34484738
PMCPMC8411620
OpenAlexW3198280696

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.