Evidence map›Paper›PMID 34484686›Full record

ArticleToxicology research2021

Comparison between

Areeg Abd-Elrazek, Hadeer Shapana, Wafaa Shukry, Doaa Galilah

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Nephrotoxicity in cancer treatment: An update.Advances in cancer research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Areeg Abd-ElrazekDepartment of Physiology, National Organization for Drug Control and Research (NODCAR), 7 Abu Hazem Rd., Al-Haram St.; Madkour Station Pyramids, Giza, Egypt.ORCID https://orcid.org/0000-0002-0995-1983
Hadeer ShapanaBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Wafaa ShukryBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Doaa GalilahBotany Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Mansoura University · EGNational Organization for Drug Control and Research · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up-regulation of NF-kB and depletion of glutathione are acceptable mechanisms of Ifosfamide (IFO) renal toxicity. This investigation elucidates the role of free radicals, inflammatory and apoptotic markers in ifosfamide-induced rentoxicity and the protection of

Indexed as

AnnonaBAXBcl-2caspase-3iNOSNF-kBoxidative stress

Identifiers

PMID34484686
PMCPMC8403598
OpenAlexW3196028697

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.