Evidence map›Paper›PMID 34484681›Full record

ArticleToxicology research2021

Nitric oxide mitigates thalidomide-induced abnormalities during germination and development of fennel seeds.

Akila Swaminathan, Koneti Brahma Kalyani, Senthil Kumar Sudhagar, Srinivasan Bhuvaneswari, S Thupali Nagalatha, T Leon Stephan Raj, Venil N Sumantran, Suvro Chatterjee

Open access · bronzeAbstract read
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In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Akila SwaminathanVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
Koneti Brahma KalyaniVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
Senthil Kumar SudhagarVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
Srinivasan BhuvaneswariVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
S Thupali NagalathaVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
T Leon Stephan RajDepartment of Botany, St. Xavier's College, Palayamkottai, Tirunelveli - 627002, India.
Venil N SumantranVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
Suvro ChatterjeeVascular Biology lab, AU-KBC Research Centre, Anna University, Madras Institute of Technology Campus, Chrompet, Chennai-600044, India.
Anna University, Chennai · INSt Xavier’s College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thalidomide causes teratogenic effects in several animal species and in humans. Accordingly, the World Health Organization banned thalidomide when mothers who took thalidomide during pregnancy delivered abnormal fetuses. After four decades, thalidomide underwent drug "re-purposing" since its antiangiogenic and immunomodulatory effects were therapeutic for multiple myeloma. There are no reports of thalidomide's effects on prokaryotes, but it showed teratogenic effects in

Indexed as

abnormalitiescGMPfennel seednitric oxidethalidomide

Identifiers

PMID34484681
PMCPMC8403600
OpenAlexW3187786826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.