Evidence map›Paper›PMID 34484676›Full record

ArticleToxicology research2021

Lactate and blood ammonia on admission as biomarkers to predict the prognosis of patients with acute mushroom poisoning and liver failure: a retrospective study.

Yanguo Gao, Hongqiao Zhang, Hua Zhong, Suosuo Yang, Qiuyan Wang

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Recent Advances in Toxic Wild Mushroom Distribution and Social Epidemiology.International journal of environmental research and public health · 2026
    Review
  3. Observational
  4. International journal of molecular sciences · 2026
    Article
  5. Article
  6. Risk factors for death in patients with acute diquat poisoning.World journal of emergency medicine · 2025
    Article
  7. Article
  8. Article
  9. Role of lactate and lactate metabolism in liver diseases (Review).International journal of molecular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yanguo GaoDepartment of Neurology, Xinhua Hospital Affiliated to Dalian University, No. 156 Wansui Street, Shahekou District, Dalian, China.
Hongqiao ZhangDepartment of Emergency, the First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Xigang District Dalian, China.
Hua ZhongDepartment of Medical Record, the First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Xigang District Dalian, China.
Suosuo YangDepartment of Emergency, the First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Xigang District Dalian, China.
Qiuyan WangDepartment of Emergency, the First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Xigang District Dalian, China.
First Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CNDalian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of liver damage induced by mushroom poisoning is still challenging. This study aims to screen the early biological indexes that could predict acute mushroom poisoning with liver damage. The patients with acute mushroom poisoning and liver damage admitted to The First Affiliated Hospital of Dalian Medical University,China from July 2007 to August 2017 were analyzed retrospectively. A total of 66 patients were enrolled in this study, with 44 and 22 patients in the liver injury group and liver failure group, respectively. Ten patients in the liver failure group died, with a mortality of 45.5% in this group. Multivariable Cox regression showed that the blood ammonia (NH3) and lactic acid (Lac) at the time of admission were independently associated with the in-hospital time to death for patients with liver failure induced by mushroom poisoning. Lactate and blood ammonia at the time of admission could be used to predict the prognosis of patients with acute mushroom poisoning and liver failure.

Indexed as

biomarkersblood ammonialactateliver failuremushroom poisoning

Identifiers

PMID34484676
PMCPMC8403588
OpenAlexW3186600326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.