Evidence map›Paper›PMID 34484624›Full record

ArticleClinics in orthopedic surgery2021

Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography and Magnetic Resonance Imaging for Adverse Local Tissue Reactions near Metal Implants after Total Hip Arthroplasty: A Preliminary Report.

Makoto Kimura, Nobuhiro Kaku, Yuta Kubota, Hiroaki Tagomori, Hiroshi Tsumura

Open access · diamondAbstract read
In one paragraph

Article in Clinics in orthopedic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Makoto KimuraDepartment of Orthopedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.ORCID https://orcid.org/0000-0002-7190-6075
Nobuhiro KakuDepartment of Orthopedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.ORCID https://orcid.org/0000-0002-4041-1870
Yuta KubotaDepartment of Orthopedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.ORCID https://orcid.org/0000-0003-1426-1482
Hiroaki TagomoriDepartment of Orthopedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.ORCID https://orcid.org/0000-0002-6185-0098
Hiroshi TsumuraDepartment of Orthopedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.ORCID https://orcid.org/0000-0002-5384-822X
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlain computed tomography (CT) and magnetic resonance imaging (MRI) are useful for diagnosing adverse local tissue reactions after metal-on-metal total hip arthroplasty (THA), but metal artifacts can hamper radiological assessments near the implants. We sought to clarify the usefulness of 18F-fluorodeoxyglucose positron-emission tomography (18F-FDG-PET) CT and MRI in the periprosthetic region, which is difficult to assess after THA due to metal artifacts.

methodsWe performed preoperative 18F-FDG-PET/CT and 18F-FDG-PET/MRI, as well as plain CT and MRI, in 11 metal-on-metal THA patients who underwent revision surgery.

resultsMost patients showed high FDG uptake in the metal artifact areas and pseudotumors in the 18-F-FDG-PET/CT and 18-F-FDG-PET/MRI scans. Intraoperative intra-articular macroscopic and histopathological intra-articular granulation tissue findings were suggestive of adverse local tissue reaction.

conclusionsThe enhanced uptake in the metal artifact areas seemed to reflect adverse local tissue reaction. Therefore, 18F-FDG-PET/CT and 18-F-FDG-PET/MRI can be useful for the auxiliary diagnosis of adverse local tissue reactions after metal-on-metal THA.

Indexed as

Arthroplasty, Replacement, HipAgedFemaleFluorodeoxyglucose F18Hip JointHumansMagnetic Resonance ImagingMaleMetalsMiddle AgedPositron Emission Tomography Computed TomographyProstheses and ImplantsReoperationFluorodeoxyglucose F18MetalsArthroplastyComputed tomographyFluorodeoxyglucose F18Metal-on-metal joint prosthesesPositron-emission tomography

Identifiers

PMID34484624
PMCPMC8380523
OpenAlexW3193463973

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.