Evidence map›Paper›PMID 34484433›Full record

ArticlePolymer chemistry2021

Determining Michael Acceptor Reactivity from Kinetic, Mechanistic, and Computational Analysis for the Base-catalyzed Thiol-Michael Reaction.

Sijia Huang, Kangmin Kim, Grant M Musgrave, Marcus Sharp, Jasmine Sinha, Jeffrey W Stansbury, Charles B Musgrave, Christopher N Bowman

Abstract read
In one paragraph

Article in Polymer chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Michael Acceptors as Anti-Cancer Compounds: Coincidence or Causality?International journal of molecular sciences · 2024
    Review
  4. Review
  5. Click Step-Growth Polymerization andAccounts of chemical research · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sijia HuangDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Kangmin KimDepartment of Chemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Grant M MusgraveDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Marcus SharpDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Jasmine SinhaDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Jeffrey W StansburyDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Charles B MusgraveDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.
Christopher N BowmanDepartment of Chemical and Biological Engineering, University of Colorado Boulder, 596 UCB, Boulder, CO 80309-0596, United States.

Funding

A one-part free radical initiator system to enable visible light-activated polymerization with post-exposure dark cure and extensive, athermal shadow cure behaviorR21DE028017 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI STANSBURY, JEFFREY W. · 2019 to 2020
$414k
NIDCR NIH HHS R21 DE028017
6 · The paper itself

Abstract

A combined experimental and computational study of the reactivities of seven commonly used Michael acceptors paired with two thiols within the framework of photobase-catalyzed thiol-Michael reactions is reported. The rate coefficients of the propagation (k

Identifiers

PMID34484433
PMCPMC8409055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.