ReviewTherapeutic advances in gastroenterology2021
Autoimmune gastritis, with or without pernicious anemia: epidemiology, risk factors, and clinical management.
Review in Therapeutic advances in gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06272500 (Safety and Efficacy Study of Betaine Hydrochloride in Treating Hypergastrinemia in Patients With Autoimmune Gastritis.), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy Study of Betaine Hydrochloride in Treating Hypergastrinemia in Patients With Autoimmune Gastritis.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- The role of autoimmune gastritis in gastric cancer risk: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- Atrophic Gastritis in a Multiethnic U.S. Population-Divergence Between Autoimmune and Non-autoimmune Etiologies.Digestive diseases and sciences · 2026Article
- Endoscopic spectrum of autoimmune gastritis across disease stages: a focus on Barrett's esophagus and ME-NBI features.Frontiers in immunology · 2026Article
- Knowledge gaps, psychological burden, and patient-reported symptom severity and daily functioning in autoimmune gastritis: a observational survey of Chinese patients.Frontiers in medicine · 2026Article
- Diagnostic value of a serum four-biomarker panel for atrophic gastritis in women under 60 years of age.Frontiers in medicine · 2026Article
- Case Report: Collagenous gastritis presenting with refractory dyspepsia and diffuse gastric atrophic-appearing changes.Frontiers in medicine · 2026Article
- Newborn Screening Alone Cannot Prevent Most Cases of Severe Vitamin B12 Deficiency in the First Year of Life.Nutrients · 2025Article
- Autoimmune gastritis: clinical and histological study in a Peruvian population.BMC gastroenterology · 2025Article
- Gyrus-like endoscopic changes in autoimmune gastritis with pastWorld journal of gastrointestinal endoscopy · 2025Article
- Article
- Autoimmune chronic atrophic gastritis: association between chronic proton pump inhibitors use and more severe atrophy and gastric intestinal metaplasia.European journal of gastroenterology & hepatology · 2025Article
- Addressing the Gaps in the Vitamin B12 Deficiency 2024 NICE Guidelines: Highlighting the Need for Better Recognition, Diagnosis, and Management of Pernicious Anaemia.European journal of clinical nutrition · 2025Review
- Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function.Journal of translational autoimmunity · 2025Review
- Gastric cancer in patients withWorld journal of gastrointestinal oncology · 2025Article
- Gastric Cancer Screening in the United States: A Review of Current Evidence, Challenges, and Future Perspectives.The American journal of gastroenterology · 2025Review
- A Case of Synchronous and Metachronous Gastric Neoplasms Associated With Autoimmune Gastritis.Cureus · 2025Article
- Masked vitamin B12 deficiency in pernicious anaemia: A diagnostic trap due to assay interference-Case report.SAGE open medical case reports · 2025Article
- Endoscopic and clinical characteristics of autoimmune atrophic gastritis: Retrospective study.Endoscopy international open · 2025Article
- Burden of anemia in the United States from 1990 to 2019: a systematic analysis of the Global Burden of Disease Study 2019.Frontiers in public health · 2025Review
- Case Report: Reversible chorea arising from severe vitamin B12 deficiency due to autoimmune gastritis: a comprehensive case study.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Autoimmune gastritis (AIG) is a chronic immune-mediated, inflammatory condition that involves the destruction of the gastric oxyntic mucosa through the autoimmune-mediated loss of parietal cells, with replacement by atrophic and metaplastic tissue. Diagnosing AIG is important, given the need for ongoing clinical management and vigilance with respect to downstream complications, the most serious of which is gastric adenocarcinoma. Other clinical consequences include gastric neuroendocrine tumors, consequences related to decreased gastric acid and decreased intrinsic factor due to parietal cell destruction and antibodies against intrinsic factor (e.g. micronutrient deficiencies), as well as concomitant autoimmune disorders. Considering the prevalence of AIG and the potential for severe clinical outcomes, it is important to engage in efforts to reduce practice pattern variability related to diagnosis and management. Accordingly, herein, we review of the epidemiology, pathogenesis, clinical presentation of AIG, including both gastric and extragastric manifestations, and provide an overview of clinical management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.