ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2021
Assessment of pain between sedated and unsedated colonoscopy: Double-blind randomized clinical trail.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Patient-reported outcomes and measures applied in individuals undergoing colonoscopy surveillance for colorectal cancer: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Psychological intervention for anxiety in patients undergoing colonoscopy: a randomized controlled trial protocol.BMC psychology · 2026Article
- Bowel Preparation Burden, Rectal Pain and Abdominal Discomfort: Perspective of Participants Undergoing CT Colonography and Colonoscopy.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Sedated Colonoscopy may not be Beneficial for Polyp/Adenoma Detection.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColonoscopy plays a vital role for the diagnosis and treatment of colonic diseases but can be associated with anxiety and discomfort or pain. We tested whether unsedated colonoscopy impacts quality indicators and investigated predictors of pain during colonoscopy. MATERIALS AND
methodsThis randomized controlled trial was performed on candidates for elective colonoscopy at AL Zahra Hospital, Isfahan at 2018-2019. Balanced block randomization was used to allocate 275 cases into two groups. At finally, 124 patients in case and 122 patients in control group enrolled in analysis. Patients in the sedation group received midazolam with/out pethidine before colonoscopy. Pain intensity in rectal examination (PIREX), preprocedural anxiety, pain intensity during colonoscopy, hemodynamics, duration of colonoscopy, polyp detection rate, cecal intubation rate, bloating within 24 h after colonoscopy, and willingness to repeat colonoscopy were assessed and compared between two groups.
resultsCompared to the group with sedation, cecal intubation time was shorter and bloating was less frequent (7% vs. 16%,
conclusionThe assessment of pain intensity during rectal examination may help to identify patients who can benefit from sedation during colonoscopy. Colonoscopy with sedation does not seem to have a negative impact on colonoscopy quality indicators, and may even reduce cecal intubation time and bloating following procedure.
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