Evidence map›Paper›PMID 34484351›Full record

ArticleJournal of contemporary brachytherapy2021

Eligibility criteria according to EAU/ESTRO/SIOG guidelines for exclusive iodine-125 brachytherapy for intermediate-risk prostate adenocarcinoma patients: impact on relapse-free survival.

Sophie Robin, Sylvie Chabaud, Anne-Agathe Serre, Béatrice Bringeon, Sébastien Clippe, François Rocher, Olivier Desmettre, Gabriel Bringeon, Frédéric Gassa, Pascal Pommier

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Ultra-low dose rate brachytherapy (uLDR-BT) in treatment of patients with unfavorable intermediate-risk group prostate cancer - retrospective analysis.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sophie RobinDepartment of Radiation Oncology, Centre Léon Bérard, Lyon, France.
Sylvie ChabaudBiostatistics Unit, Centre Léon Bérard, Lyon, France.
Anne-Agathe SerreDepartment of Radiation Oncology, Centre Léon Bérard, Lyon, France.
Béatrice BringeonDepartment of Anatomopathology, Infirmerie Protestante, Lyon, France.
Sébastien ClippeDepartment of Radiation Oncology, Centre Marie Curie, Valence, France.
François RocherDepartment of Radiation Oncology, Sainte Marie, Châlon Sur Saône, France.
Olivier DesmettreDepartment of Urology, Infirmerie Protestante, Lyon, France.
Gabriel BringeonDepartment of Urology, Infirmerie Protestante, Lyon, France.
Frédéric GassaDepartment of Radiation Oncology, Centre Léon Bérard, Lyon, France.
Pascal PommierDepartment of Radiation Oncology, Centre Léon Bérard, Lyon, France.
Centre Léon Bérard · FRInfirmerie Protestante · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIodine-125 ( MATERIAL AND

methodsAmong 547 patients treated with

resultsOf the 149 IR patients, 112 were classified as favorable, with 69 cases eligible to BT according to EAU/ESTRO/SIOG guidelines, and 37 patients were identified as unfavorable as per NCCN. Androgen deprivation therapy (ADT) was applied in 6 patients only. Percentage of positive biopsy cores were ≤ 33% and ≥ 50% for 119 and 11 patients, respectively. With a median follow-up of 8.5 years, 30 patients experienced a relapse. 10-year overall survival, progression-free survival (PFS), and relapse-free survival (RFS) were 84% (95% CI: 75-90%), 66% (95% CI: 56-75%), and 77% (95% CI: 67-84%), respectively. Failure to meet EAU/ESTRO/SIOG criteria was significantly associated with a lower RFS (

conclusionsBrachytherapy is an effective treatment for selected IR-PCA cases. Patients who were not eligible according to EAU/ESTRO/SIOG guidelines demonstrated a lower RFS.

Indexed as

brachytherapyguidelinesintermediate-riskprognostic criteriaprostate

Identifiers

PMID34484351
PMCPMC8407263
OpenAlexW3193918567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.