Evidence map›Paper›PMID 34484304›Full record

ArticleFrontiers in genetics2021

Genetic Polymorphism of Vitamin D Family Genes

Minxian Wang, Ru Zhang, Min Wang, Liuxin Zhang, Yajie Ding, Zongzhe Tang, Hongliang Wang, Wei Zhang, Yue Chen, Jie Wang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Impact ofCell cycle (Georgetown, Tex.) · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Minxian WangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Ru ZhangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Min WangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Liuxin ZhangThe Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Yajie DingDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Zongzhe TangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Hongliang WangNinghai Road Community Health Service Center of Nanjing, Nanjing, China.
Wei ZhangDepartment of Epidemiology, Shanghai Cancer Institute, Shanghai, China.
Yue ChenDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Jie WangDepartment of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNNanjing Health and Health Commission · CNShanghai Cancer Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have highlighted the important role of vitamin D and calcium pathway genes in immune modulation, cell differentiation and proliferation, and inflammation regulation, all closely implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Objective: This study aims to investigate whether 11 candidate single nucleotide polymorphisms (SNPs) in vitamin D and calcium pathway genes ( Methods: In this case-control study, a total of 3,023 subjects were enrolled, including 1,114 NAFLD cases and 1,909 controls. Eleven genetic variants in Results: After adjusting for age, gender, and metabolic measures, we identified that Conclusion: The polymorphisms of vitamin family genes

Indexed as

cytochrome P450 family 24 subfamily A member 1 genecytochrome P450 family 27 subfamily B member 1 genenon-alcoholic fatty liver diseasepolymorphismrisk

Identifiers

PMID34484304
PMCPMC8415785
OpenAlexW3194134641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.